HitPredict

Interactor 1: PF21A (Q96BD5)
PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80)
Gene: PHF21A

Interactor 2: TRPS1 (Q9UHF7)
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)
Gene: TRPS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 680 Hs			1 1281
+	Hs
		1351293 CHD5_HUMAN (255-617): 1.44e-43: 171: 16.79		TRPS1_HUMAN (1-1281): 0: 1890: 100.00
+	Hs
		1133032 CHD4_HUMAN (255-650): 3.89e-43: 170: 14.51		TRPS1_HUMAN (1-1281): 0: 1890: 100.00
+	Hs
		1088604 CHD3_HUMAN (297-617): 2.53e-41: 164: 16.57		TRPS1_HUMAN (1-1281): 0: 1890: 100.00
+	Hs
		1104577 CHD4_HUMAN (255-650): 3.89e-43: 170: 14.51		IKZF1_HUMAN (781-1272): 1.14e-106: 348: 19.45
+	Hs
		1088324 CHD3_HUMAN (297-617): 2.53e-41: 164: 16.57		IKZF1_HUMAN (781-1272): 1.14e-106: 348: 19.45
+	Hs
		1133040 CHD4_HUMAN (255-650): 3.89e-43: 170: 14.51		IKZF2_HUMAN (800-1270): 1.1e-83: 285: 16.20
+	Mm
		607342 TRI33_MOUSE (2-648): 1.01e-86: 296: 15.96		GATA1_MOUSE (804-1033): 5.2e-40: 155: 20.21
+	Hs
		1133041 CHD4_HUMAN (255-650): 3.89e-43: 170: 14.51		IKZF3_HUMAN (850-1268): 1e-81: 279: 18.63
+	Hs
		1132971 CHD4_HUMAN (255-650): 3.89e-43: 170: 14.51		IKZF4_HUMAN (771-1268): 1.59e-79: 275: 18.28
+	Hs
		1088612 CHD3_HUMAN (297-617): 2.53e-41: 164: 16.57		IKZF3_HUMAN (850-1268): 1e-81: 279: 18.63
+	Mm
		148462 Q8BR71_MOUSE (298-617): 3.86e-38: 153: 15.84		IKZF3_MOUSE (783-1268): 8.54e-82: 279: 17.04
+	Mm
		148616 TRI33_MOUSE (2-648): 1.01e-86: 296: 15.96		GATA2_MOUSE (821-1072): 5.48e-28: 121: 19.48
+	Hs
		851661 KDM5D_HUMAN (165-655): 8.75e-66: 238: 16.30		GATA4_HUMAN (870-1060): 3.76e-45: 171: 28.36
+	Hs
		180707 TIF1A_HUMAN (2-647): 2.12e-79: 275: 14.56		GATA2_HUMAN (821-1072): 2.63e-27: 119: 20.60
+	Hs
		851693 BAZ2A_HUMAN (4-648): 2.66e-53: 200: 11.71		GATA4_HUMAN (870-1060): 3.76e-45: 171: 28.36
+	Hs
		851559 CHD4_HUMAN (255-650): 3.89e-43: 170: 14.51		GATA4_HUMAN (870-1060): 3.76e-45: 171: 28.36
+	Mm
		607339 CHD4_MOUSE (255-650): 9.38e-43: 168: 14.51		GATA1_MOUSE (804-1033): 5.2e-40: 155: 20.21
+	Hs
		851646 RSF1_HUMAN (156-578): 5.97e-34: 141: 16.59		GATA4_HUMAN (870-1060): 3.76e-45: 171: 28.36