HitPredict

Interactor 1: IMA4 (O00505)
Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma)
Gene: KPNA3

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 521 Hs			1 758
+	Hs
		142481 IMA3_HUMAN (1-521): 3.11e-157: 459: 85.80		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		529388 IMA1_HUMAN (3-521): 3.15e-142: 421: 48.67		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		253579 IMA7_HUMAN (4-520): 7.74e-139: 413: 46.43		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		179021 IMA6_HUMAN (4-520): 2.03e-133: 399: 46.73		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		529389 IMA5_HUMAN (5-520): 9.79e-132: 395: 45.52		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		138755 IMA4_HUMAN (1-521): 1.86e-160: 468: 100.00		CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46
+	Hs
		142611 IMA3_HUMAN (1-521): 3.11e-157: 459: 85.80		CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46
+	Hs
		911062 IMA1_HUMAN (3-521): 3.15e-142: 421: 48.67		CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46
+	Hs
		911348 IMA5_HUMAN (5-520): 9.79e-132: 395: 45.52		CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46