HitPredict

Interactor 1: TONSL (Q96HA7)
Tonsoku-like protein (Inhibitor of kappa B-related protein) (I-kappa-B-related protein) (IkappaBR) (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2)
Gene: TONSL

Interactor 2: H2AW (Q9P0M6)
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Gene: MACROH2A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1378 Hs			1 372
+	Hs
		277778 TONSL_HUMAN (1-1378): 0: 630: 100.00		H2AY_HUMAN (1-371): 8.22e-156: 444: 66.31
+	Hs
		591787 TONSL_HUMAN (1-1378): 0: 630: 100.00		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		1162867 TONSL_HUMAN (1-1378): 0: 630: 100.00		H2A2C_HUMAN (1-126): 7.61e-64: 201: 61.24
+	Hs
		1232710 TONSL_HUMAN (1-1378): 0: 630: 100.00		H2A2A_HUMAN (1-126): 4.29e-64: 201: 62.02
+	Hs
		1392821 TONSL_HUMAN (1-1378): 0: 630: 100.00		H2AJ_HUMAN (1-126): 1.06e-63: 201: 60.47
+	Hs
		419136 TONSL_HUMAN (1-1378): 0: 630: 100.00		H2A1B_HUMAN (1-126): 6.68e-64: 201: 60.47
+	Hs
		502480 TONSL_HUMAN (1-1378): 0: 630: 100.00		H2A1_HUMAN (1-126): 6.4e-64: 201: 60.47
+	Hs
		277794 BARD1_HUMAN (523-674): 2.97e-40: 163: 36.18		H2AY_HUMAN (1-371): 8.22e-156: 444: 66.31
+	Hs
		277493 TNKS1_HUMAN (116-369): 1.17e-09: 65.2: 8.88		H2AY_HUMAN (1-371): 8.22e-156: 444: 66.31
+	Hs
		1396093 TANC1_HUMAN (72-671): 1.77e-74: 276: 13.90		H2A1H_HUMAN (1-125): 5.04e-64: 201: 60.94
+	Hs
		591809 BARD1_HUMAN (523-674): 2.97e-40: 163: 36.18		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		1162877 BARD1_HUMAN (523-674): 2.97e-40: 163: 36.18		H2A2C_HUMAN (1-126): 7.61e-64: 201: 61.24
+	Hs
		419159 BARD1_HUMAN (523-674): 2.97e-40: 163: 36.18		H2A1B_HUMAN (1-126): 6.68e-64: 201: 60.47
+	Hs
		591723 ANKH1_HUMAN (299-583): 1.84e-17: 91.2: 17.24		H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14
+	Hs
		419070 ANKH1_HUMAN (299-583): 1.84e-17: 91.2: 17.24		H2A1B_HUMAN (1-126): 6.68e-64: 201: 60.47
+	Hs
		502420 ANKH1_HUMAN (299-583): 1.84e-17: 91.2: 17.24		H2A1_HUMAN (1-126): 6.4e-64: 201: 60.47
+	Hs
		1330768 ANR31_HUMAN (503-636): 7.74e-13: 75.9: 36.69		H2A1H_HUMAN (1-125): 5.04e-64: 201: 60.94