HitPredict

Interactor 1: Q96II5 (Q96II5)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
Gene: ARAF

Interactor 2: Q9BPW0 (Q9BPW0)
Serine/threonine-protein phosphatase (EC 3.1.3.16)
Gene: PPP5C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 609 Hs			1 484
+	Hs
		401375 RAF1_HUMAN (6-609): 0: 560: 59.80		Q9BPW0_HUMAN (1-484): 0: 544: 100.00
+	Hs
		578449 BRAF_HUMAN (3-607): 0: 563: 55.88		PP2AA_HUMAN (188-483): 9.79e-170: 482: 40.33
+	Hs
		400629 RAF1_HUMAN (6-609): 0: 560: 59.80		PP2AA_HUMAN (188-483): 9.79e-170: 482: 40.33
+	Gg
		873659 BRAF_CHICK (3-607): 0: 556: 55.54		PP2AA_CHICK (187-483): 4.74e-157: 449: 38.59
+	Hs
		400595 RAF1_HUMAN (6-609): 0: 560: 59.80		PP1B_HUMAN (194-482): 5.71e-154: 442: 36.90
+	Hs
		578438 BRAF_HUMAN (3-607): 0: 563: 55.88		PP1A_HUMAN (201-479): 1.05e-152: 439: 38.93
+	Hs
		400398 RAF1_HUMAN (6-609): 0: 560: 59.80		PP1G_HUMAN (195-481): 1.83e-152: 438: 37.85
+	Mm
		700333 BRAF_MOUSE (3-607): 0: 558: 56.13		PP1A_MOUSE (201-479): 4.24e-153: 440: 38.93
+	Hs
		578440 BRAF_HUMAN (3-607): 0: 563: 55.88		PP2AB_HUMAN (180-483): 3.27e-149: 429: 38.69
+	Hs
		400606 RAF1_HUMAN (6-609): 0: 560: 59.80		PP2AB_HUMAN (180-483): 3.27e-149: 429: 38.69
+	Mm
		700335 BRAF_MOUSE (3-607): 0: 558: 56.13		PP2AB_MOUSE (180-483): 3.27e-149: 429: 38.69
+	Mm
		994004 KSR1_MOUSE (50-609): 7.77e-126: 393: 26.30		PP2AA_MOUSE (188-483): 1.22e-169: 481: 40.33
+	Hs
		977538 KSR1_HUMAN (50-609): 3.3e-118: 374: 24.56		PP2AB_HUMAN (180-483): 3.27e-149: 429: 38.69
+	Hs
		463046 YES_HUMAN (292-571): 3.94e-104: 327: 31.34		PP1B_HUMAN (194-482): 5.71e-154: 442: 36.90
+	Hs
		557202 SRC_HUMAN (285-571): 2.55e-104: 327: 30.24		PP2AB_HUMAN (180-483): 3.27e-149: 429: 38.69
+	Hs
		1250422 KSR2_HUMAN (306-587): 3.23e-45: 174: 36.30		Q9BPW0_HUMAN (1-484): 0: 544: 100.00
+	Hs
		916672 KSR2_HUMAN (306-587): 3.23e-45: 174: 36.30		PPP5_HUMAN (1-482): 0: 544: 99.17