Interactor 1: NECT4 (Q96NY8)
Nectin-4 (Ig superfamily receptor LNIR) (Nectin cell adhesion molecule 4) (Poliovirus receptor-related protein 4) [Cleaved into: Processed poliovirus receptor-related protein 4]
Gene: NECTIN4
Interactor 2: NECT4 (Q96NY8)
Nectin-4 (Ig superfamily receptor LNIR) (Nectin cell adhesion molecule 4) (Poliovirus receptor-related protein 4) [Cleaved into: Processed poliovirus receptor-related protein 4]
Gene: NECTIN4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.51 | 1.00 | 0.716 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22902367 |
| Identification Methods | x-ray crystallography, surface plasmon resonance, cosedimentation in solution |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C2-set_2~C2-set_2, C2-set_2~Ig_3, C2-set_2~V-set, Ig_3~Ig_3, Ig_3~V-set, V-set~V-set |
| Common GO terms | GO:0001618 - virus receptor activity GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and 3 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025