Protein: NECT4
Nectin-4 (Ig superfamily receptor LNIR) (Nectin cell adhesion molecule 4) (Poliovirus receptor-related protein 4) [Cleaved into: Processed poliovirus receptor-related protein 4]

Gene: NECT4, NECTIN4
Organism: Homo sapiens
Interactions: 27
UniProt ID: Q96NY8

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0005886 - plasma membrane
GO:0005912 - adherens junction
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1144344

NECT1
Nectin-1

3

16

Small-scale

0.870

High

1193161

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

1

3

Small-scale

0.724

High

1366770

NECT2
Nectin-2

1

18

Small-scale

0.724

High

1399294

NECT4
Nectin-4

1

17

Small-scale

0.716

High

1398997

ZN582
Zinc finger protein 582

3

0

High-throughput

0.709

High

1124222

EI2BA
Translation initiation factor eIF2B subunit alpha

3

5

High-throughput

0.667

High

1331350

ENAH
Protein enabled homolog

3

14

High-throughput

0.667

High

1399299

EVL
Ena/VASP-like protein

3

7

High-throughput

0.667

High

1399296

PIGU
GPI-anchor transamidase component PIGU

3

0

High-throughput

0.638

High

556291

CADH1
Cadherin-1

1

11

High-throughput

0.618

High

890155

EI2BB
Translation initiation factor eIF2B subunit beta

3

5

High-throughput

0.609

High

1212165

DPS1
All trans-polyprenyl-diphosphate synthase PDSS1

3

1

High-throughput

0.609

High

1399297

EI2BG
Translation initiation factor eIF2B subunit gamma

3

2

High-throughput

0.609

High

1399300

EI2BD
Translation initiation factor eIF2B subunit delta

3

5

High-throughput

0.609

High

1292865

STING
Stimulator of interferon genes protein

1

2

High-throughput

0.515

High

593691

BGAL
Beta-galactosidase

1

0

High-throughput

0.513

High

1348179

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.513

High

936415

AFAD
Afadin

1

20

Small-scale

0.508

High

1095929

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

3

High-throughput

0.489

High

1399298

PICK1
PRKCA-binding protein

1

4

Small-scale

0.481

High

528707

PPGB
Lysosomal protective protein

1

1

High-throughput

0.479

High

1399295

CF062
Uncharacterized protein C6orf62

3

0

High-throughput

0.347

High

1399301

FBX10
F-box only protein 10

3

0

High-throughput

0.347

High

940168

RRP1
Ribosomal RNA processing protein 1 homolog A

2

0

High-throughput

0.318

High

1205426

DB121
Beta-defensin 121

2

0

High-throughput

0.316

High

1015283

ERH
Enhancer of rudimentary homolog

1

0

Small-scale

0.261

Low


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Last updated: 11Aug2025