HitPredict

Interactor 1: NED4L (Q96PU5)
E3 ubiquitin-protein ligase NEDD4-like (EC 2.3.2.26) (EC 2.3.2.36) (HECT-type E3 ubiquitin transferase NED4L) (NEDD4.2) (Nedd4-2)
Gene: NEDD4L

Interactor 2: S22AB (Q9NSA0)
Solute carrier family 22 member 11 (Organic anion transporter 4) (OAT4) (Organic anion:dicarboxylate exchanger OAT4)
Gene: SLC22A11

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26740304, 30453017
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016324 - apical plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 975 Hs			1 550
+	Hs
		1196211 NED4L_HUMAN (1-975): 0: 1042: 100.00		S22A6_HUMAN (1-538): 4.49e-128: 387: 42.30
+	Hs
		1308943 NED4L_HUMAN (1-975): 0: 1042: 100.00		S22A9_HUMAN (1-550): 6.06e-128: 387: 41.80
+	Hs
		1349590 NED4L_HUMAN (1-975): 0: 1042: 100.00		S22A8_HUMAN (1-549): 2.62e-117: 359: 40.55
+	Hs
		861635 NEDD4_HUMAN (100-975): 0: 801: 61.35		S22A6_HUMAN (1-538): 4.49e-128: 387: 42.30
+	Rn
		205704 NEDD4_RAT (13-975): 0: 808: 55.39		S22A6_RAT (1-532): 1.13e-123: 375: 40.15
+	Hs
		861694 NEDD4_HUMAN (100-975): 0: 801: 61.35		S22A8_HUMAN (1-549): 2.62e-117: 359: 40.55
+	Hs
		1394606 ITCH_HUMAN (9-972): 0: 795: 32.96		S22A4_HUMAN (2-547): 8.43e-114: 350: 27.04
+	Sc
		808962 RSP5_YEAST (22-455): 1.83e-28: 125: 17.24		HXT6_YEAST (136-538): 9.59e-75: 249: 18.10