HitPredict

Interactor 1: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Interactor 2: CPAP (Q9HC77)
Centrosomal P4.1-associated protein (Centromere protein J) (CENP-J) (Centrosome assembly and centriole elongation protein) (LAG-3-associated protein) (LYST-interacting protein 1)
Gene: CPAP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.523

Property	Details
Experiments	16713569
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2517 Hs			1 1338
+	Hs
		587777 CIC_HUMAN (1-2517): 0: 945: 100.00		DESP_HUMAN (653-1103): 1.51e-09: 64.9: 15.82
+	Hs
		872350 SOX2_HUMAN (1073-1308): 2.24e-57: 204: 24.05		PLEC_HUMAN (256-1192): 4.91e-28: 125: 6.72
+	Hs
		773125 SOX2_HUMAN (1073-1308): 2.24e-57: 204: 24.05		MYH10_HUMAN (63-774): 1.93e-19: 97.4: 8.65
+	Hs
		587588 SOX2_HUMAN (1073-1308): 2.24e-57: 204: 24.05		DESP_HUMAN (653-1103): 1.51e-09: 64.9: 15.82
+	Hs
		1143307 SRRM2_HUMAN (850-2517): 1.87e-29: 131: 7.91		PLEC_HUMAN (256-1192): 4.91e-28: 125: 6.72
+	Hs
		1143196 KMT2C_HUMAN (1133-2516): 1.63e-13: 79.5: 8.66		PLEC_HUMAN (256-1192): 4.91e-28: 125: 6.72
+	Hs
		1273851 MICA3_HUMAN (2116-2494): 2.89e-09: 65.1: 11.35		MY18A_HUMAN (505-1181): 3.94e-21: 103: 10.61
+	Hs
		772875 MICA3_HUMAN (2116-2494): 2.89e-09: 65.1: 11.35		MYH9_HUMAN (570-1196): 7.95e-21: 102: 8.50
+	Hs
		772931 TITIN_HUMAN (750-1458): 4.36e-09: 64.6: 9.03		MYH9_HUMAN (570-1196): 7.95e-21: 102: 8.50
+	Hs
		772749 ANK2_HUMAN (535-2223): 9.82e-09: 63.4: 10.19		MYH9_HUMAN (570-1196): 7.95e-21: 102: 8.50
+	Hs
		773158 ANK2_HUMAN (535-2223): 9.82e-09: 63.4: 10.19		MYH10_HUMAN (63-774): 1.93e-19: 97.4: 8.65
+	Hs
		587751 TITIN_HUMAN (750-1458): 4.36e-09: 64.6: 9.03		DESP_HUMAN (653-1103): 1.51e-09: 64.9: 15.82