HitPredict

Interactor 1: CLCC1 (Q96S66)
Chloride channel CLIC-like protein 1 (ER anion channel 1) (ERAC1) (Mid-1-related chloride channel protein)
Gene: CLCC1

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.585

Property	Details
Experiments	35384245, 39115278, 34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 1620
+	Hs
		464036 CLCC1_HUMAN (1-551): 0: 1108: 100.00		RET_HUMAN (804-1477): 5.87e-139: 460: 23.15
+	Hs
		179630 CLCC1_HUMAN (1-551): 0: 1108: 100.00		MUSK_HUMAN (983-1391): 1.78e-119: 399: 29.98
+	Hs
		477257 CLCC1_HUMAN (1-551): 0: 1108: 100.00		ROS1_HUMAN (1039-1461): 3.97e-112: 397: 37.75
+	Hs
		439830 CLCC1_HUMAN (1-551): 0: 1108: 100.00		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		465621 CLCC1_HUMAN (1-551): 0: 1108: 100.00		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		572951 CLCC1_HUMAN (1-551): 0: 1108: 100.00		INSRR_HUMAN (1082-1384): 2.39e-70: 262: 43.46
+	Hs
		412473 CLCC1_HUMAN (1-551): 0: 1108: 100.00		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		1157036 CLCC1_HUMAN (1-551): 0: 1108: 100.00		NTRK3_HUMAN (1093-1375): 2.7e-59: 223: 39.03
+	Hs
		541647 CLCC1_HUMAN (1-551): 0: 1108: 100.00		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07