Protein: CLCC1
Chloride channel CLIC-like protein 1 (ER anion channel 1) (ERAC1) (Mid-1-related chloride channel protein)

Gene: CLCC1
Organism: Homo sapiens
Interactions: 212
UniProt ID: Q96S66

Gene Ontology (top 5):
GO:0005254 - chloride channel activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0032469 - endoplasmic reticulum calcium ion homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1251710

SPNS3
Protein spinster homolog 3

4

0

High-throughput

0.658

High

180576

PLS1
Phospholipid scramblase 1

3

0

High-throughput

0.634

High

699033

CALX
Calnexin

2

1

High-throughput

0.611

High

276249

SEM7A
Semaphorin-7A

2

0

High-throughput

0.602

High

1114080

CUL3
Cullin-3

2

0

High-throughput

0.585

High

1402399

ALK
ALK tyrosine kinase receptor

3

9

Small-scale

0.585

High

375859

RASK
GTPase KRas

2

3

High-throughput

0.584

High

540633

LAMP1
Lysosome-associated membrane glycoprotein 1

2

2

High-throughput

0.584

High

902022

RAB9A
Ras-related protein Rab-9A

2

3

High-throughput

0.584

High

1352350

RHBL4
Rhomboid-related protein 4

2

1

Small-scale

0.584

High

1311090

UBR1
E3 ubiquitin-protein ligase UBR1

2

1

High-throughput

0.574

High

951369

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

880656

LMAN1
Protein ERGIC-53

2

0

High-throughput

0.547

High

1402386

OCAD1
OCIA domain-containing protein 1

2

0

High-throughput

0.547

High

1199664

KLH22
Kelch-like protein 22

2

0

High-throughput

0.528

High

1311159

UBR2
E3 ubiquitin-protein ligase UBR2

2

1

Small-scale

0.521

High

1369934

ARHG1
Rho guanine nucleotide exchange factor 1

2

1

High-throughput

0.521

High

349542

TSN15
Tetraspanin-15

1

0

High-throughput

0.513

High

640992

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

0

High-throughput

0.513

High

934271

BI1
Bax inhibitor 1

1

0

High-throughput

0.513

High

1291665

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.513

High

1382163

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1402374

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

1402377

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

1402404

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.513

High

477257

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

8

High-throughput

0.500

High

48752

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.479

High

363747

EGFR
Epidermal growth factor receptor

1

6

High-throughput

0.479

High

374152

RASN
GTPase NRas

1

3

High-throughput

0.479

High

411014

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

7

High-throughput

0.479

High

439830

INSR
Insulin receptor

1

10

High-throughput

0.479

High

465621

IGF1R
Insulin-like growth factor 1 receptor

1

10

High-throughput

0.479

High

466426

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.479

High

541647

FGFR1
Fibroblast growth factor receptor 1

1

6

High-throughput

0.479

High

562337

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

581245

RAC2
Ras-related C3 botulinum toxin substrate 2

1

6

High-throughput

0.479

High

593475

PGFRA
Platelet-derived growth factor receptor alpha

1

4

High-throughput

0.479

High

604165

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

611305

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.479

High

631424

RAB5A
Ras-related protein Rab-5A

1

2

High-throughput

0.479

High

720689

AGTR1
Type-1 angiotensin II receptor

1

2

High-throughput

0.479

High

901510

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.479

High

939962

TPTE
Putative tyrosine-protein phosphatase TPTE

1

1

High-throughput

0.479

High

953628

RAC3
Ras-related C3 botulinum toxin substrate 3

1

6

High-throughput

0.479

High

955504

CDC42
Cell division control protein 42 homolog

1

6

High-throughput

0.479

High

962407

RHOA
Transforming protein RhoA

1

7

High-throughput

0.479

High

988632

RAC1
Ras-related C3 botulinum toxin substrate 1

1

6

High-throughput

0.479

High

1015699

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.479

High

1055081

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

9

High-throughput

0.479

High

1087251

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

1098468

DNJC3
DnaJ homolog subfamily C member 3

1

3

High-throughput

0.479

High

1163405

CAH9
Carbonic anhydrase 9

1

1

High-throughput

0.479

High

1179129

TECT1
Tectonic-1

1

2

High-throughput

0.479

High

1245120

RHDF2
Inactive rhomboid protein 2

1

1

High-throughput

0.479

High

1287417

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

High-throughput

0.479

High

1294239

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.479

High

1312227

MIRO2
Mitochondrial Rho GTPase 2

1

10

High-throughput

0.479

High

1313807

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.479

High

1381497

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.479

High

1395921

DNJC1
DnaJ homolog subfamily C member 1

1

4

High-throughput

0.479

High

1396532

CALR3
Calreticulin-3

1

1

High-throughput

0.479

High

1401677

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.479

High

1402371

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

1402375

DJC25
DnaJ homolog subfamily C member 25

1

4

High-throughput

0.479

High

1402380

SAR1A
Small COPII coat GTPase SAR1A

1

2

High-throughput

0.479

High

1402388

DJB12
DnaJ homolog subfamily B member 12

1

2

High-throughput

0.479

High

1402396

SEC63
Translocation protein SEC63 homolog

1

2

High-throughput

0.479

High

1402398

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

1402400

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

1402401

DJC16
DnaJ homolog subfamily C member 16

1

3

High-throughput

0.479

High

124452

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.458

High

174060

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

178368

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

210599

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

0

High-throughput

0.458

High

229799

CALU
Calumenin

1

0

High-throughput

0.458

High

291502

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

417696

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

418374

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

459325

CATL1
Procathepsin L

1

0

High-throughput

0.458

High

488844

FURIN
Furin

1

0

High-throughput

0.458

High

548364

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.458

High

566809

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.458

High

643036

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

693060

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

715729

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

767309

MERL
Merlin

1

0

High-throughput

0.458

High

820726

CEAM6
Cell adhesion molecule CEACAM6

1

0

High-throughput

0.458

High

837798

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

847655

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

894991

EMD
Emerin

1

0

High-throughput

0.458

High

904082

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

975190

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

1005552

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

0

High-throughput

0.458

High

1027147

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.458

High

1058606

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

1111668

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.458

High

1125616

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

1249139

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1252189

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1276285

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1308191

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.458

High

1309873

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1326998

DJC22
DnaJ homolog subfamily C member 22

1

0

High-throughput

0.458

High

1333965

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

1337641

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.458

High

1383023

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1401207

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1402368

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1402372

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1402373

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1402376

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.458

High

1402378

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1402381

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1402382

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

1402385

CC50A
Cell cycle control protein 50A

1

0

High-throughput

0.458

High

1402387

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

High-throughput

0.458

High

1402389

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

1402391

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.458

High

1402392

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1402393

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

1402394

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.458

High

1402395

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1402402

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

1402403

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

104213

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.445

High

126757

RHOD
Rho-related GTP-binding protein RhoD

1

7

High-throughput

0.437

High

179630

MUSK
Muscle, skeletal receptor tyrosine-protein kinase

1

10

High-throughput

0.437

High

188969

TMPS2
Transmembrane protease serine 2

1

1

High-throughput

0.437

High

189786

STX7
Syntaxin-7

1

1

High-throughput

0.437

High

412473

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.437

High

464036

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

7

High-throughput

0.437

High

572951

INSRR
Insulin receptor-related protein

1

10

High-throughput

0.437

High

630613

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.437

High

630944

RAB4A
Ras-related protein Rab-4A

1

1

High-throughput

0.437

High

710748

EPHA8
Ephrin type-A receptor 8

1

4

High-throughput

0.437

High

777749

VGFR3
Vascular endothelial growth factor receptor 3

1

5

High-throughput

0.437

High

900997

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.437

High

910174

RND2
Rho-related GTP-binding protein RhoN

1

8

High-throughput

0.437

High

931883

EPHA5
Ephrin type-A receptor 5

1

4

High-throughput

0.437

High

951822

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

Small-scale

0.437

High

1034324

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

8

High-throughput

0.437

High

1145070

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.437

High

1157036

NTRK3
NT-3 growth factor receptor

1

9

High-throughput

0.437

High

1235317

STYK1
Tyrosine-protein kinase STYK1

1

4

High-throughput

0.437

High

1238789

TECT3
Tectonic-3

1

2

High-throughput

0.437

High

1286879

TM11B
Transmembrane protease serine 11B

1

1

High-throughput

0.437

High

1322957

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.437

High

1360919

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

1370790

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

1

High-throughput

0.437

High

1392436

TECT2
Tectonic-2

1

2

High-throughput

0.437

High

1397146

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

2

High-throughput

0.437

High

256116

S19A2
Thiamine transporter 1

1

0

High-throughput

0.426

High

665005

ERD21
ER lumen protein-retaining receptor 1

1

0

High-throughput

0.426

High

720021

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.426

High

1180306

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.426

High

1211194

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.426

High

1236284

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1240941

S27A4
Long-chain fatty acid transport protein 4

1

0

High-throughput

0.426

High

1248491

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

1

0

High-throughput

0.426

High

1312971

S35F2
Solute carrier family 35 member F2

1

0

High-throughput

0.426

High

1316353

AGRG5
Adhesion G-protein coupled receptor G5

1

0

High-throughput

0.426

High

1359489

CTL1
Choline transporter-like protein 1

1

0

High-throughput

0.426

High

1402379

GPC5C
G-protein coupled receptor family C group 5 member C

1

0

High-throughput

0.426

High

1402383

UFSP2
Ufm1-specific protease 2

1

0

High-throughput

0.426

High

702832

5HT2C
5-hydroxytryptamine receptor 2C

1

1

High-throughput

0.407

High

704063

5HT1E
5-hydroxytryptamine receptor 1E

1

1

High-throughput

0.407

High

907107

CCR9
C-C chemokine receptor type 9

1

2

High-throughput

0.407

High

956985

CXCR4
C-X-C chemokine receptor type 4

1

2

High-throughput

0.407

High

1274083

MOT14
Monocarboxylate transporter 14

1

1

High-throughput

0.407

High

1274100

MOT9
Monocarboxylate transporter 9

1

1

High-throughput

0.407

High

1366192

LPAR1
Lysophosphatidic acid receptor 1

1

1

High-throughput

0.407

High

1402369

S1PR3
Sphingosine 1-phosphate receptor 3

1

1

High-throughput

0.407

High

1139119

DAZP2
DAZ-associated protein 2

3

0

High-throughput

0.345

High

1394254

GMCL1
Germ cell-less protein-like 1

3

0

High-throughput

0.345

High

1154218

TBCE
Tubulin-specific chaperone E

2

0

High-throughput

0.328

High

1402397

VAV3
Guanine nucleotide exchange factor VAV3

2

0

High-throughput

0.298

High

659053

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

0

High-throughput

0.279

Low

1212975

ZN684
Zinc finger protein 684

1

0

High-throughput

0.279

Low

1249539

AMTN
Amelotin

1

0

High-throughput

0.279

Low

1270611

COX15
Heme A synthase COX15

1

0

High-throughput

0.279

Low

1295636

MYLK4
Myosin light chain kinase family member 4

1

0

High-throughput

0.279

Low

1389955

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.279

Low

2142

PIOS1
Protein PIGBOS1

1

0

Small-scale

0.278

Low

185945

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.261

Low

218658

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

226177

STX6
Syntaxin-6

1

0

High-throughput

0.249

Low

302932

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.249

Low

320757

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.249

Low

580680

AMPN
Aminopeptidase N

1

0

High-throughput

0.249

Low

605786

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.249

Low

700712

PSA5
Proteasome subunit alpha type-5

1

0

Small-scale

0.249

Low

976502

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.249

Low

1004171

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.249

Low

1005002

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1045673

TF65
Transcription factor p65

1

0

High-throughput

0.249

Low

1192283

ZACN
Ligand-gated cation channel ZACN

1

0

High-throughput

0.249

Low

1204485

RNS13
Probable inactive ribonuclease-like protein 13

1

0

High-throughput

0.249

Low

1255169

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1288492

LBN
Limbin

1

0

High-throughput

0.249

Low

1293120

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1293646

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

1364216

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.249

Low

1382917

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

1402367

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.249

Low

1402370

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.249

Low

1402384

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1402390

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

567465

TCTP
Translationally-controlled tumor protein

1

0

Small-scale

0.232

Low

906339

GPC3
Glypican-3

1

0

High-throughput

0.232

Low

1048383

ACVR1
Activin receptor type-1

1

0

High-throughput

0.232

Low

1136725

LAP4A
Lysosomal-associated transmembrane protein 4A

1

0

High-throughput

0.232

Low

1325720

RIBC1
RIB43A-like with coiled-coils protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025