Interactor 1: MYSN (Q99323)
Myosin heavy chain, non-muscle (Myosin II) (Non-muscle MHC) (Zipper protein)
Gene: zip

Interactor 2: MYSN (Q99323)
Myosin heavy chain, non-muscle (Myosin II) (Non-muscle MHC) (Zipper protein)
Gene: zip

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 17901043, 17989074, 21078954
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, transmission electron microscopy, cosedimentation in solution
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IQ~IQ, IQ~Myosin_head, Myosin_head~Myosin_head, Myosin_N~Myosin_head, Myosin_head~Myosin_tail_1, Myosin_N~Myosin_tail_1, Myosin_tail_1~Myosin_tail_1
Common GO terms GO:0000146 - microfilament motor activity
GO:0000281 - mitotic cytokinesis
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
and 43 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 2057
Dm

1 2057
+ Hs
+ Rn
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025