Interactor 1: CDC5L (Q99459)
Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein)
Gene: CDC5L

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 28514442, 28666352, 29395067, 32460013, 33961781, 35271311, 31839598, 20176811, 20467437, 11101529, 20595234, 17276391, 19633697
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, far western blotting, biochemical, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Myb_Cef~Prp19
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 802
Hs

1 504
+ Hs
+ Hs
+ Dm
+ At
+ Hs
+ Sc
+ Hs
+ Mm
+ Hs

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Last updated: 11Aug2025