HitPredict

Interactor 1: CSN8 (Q99627)
COP9 signalosome complex subunit 8 (SGN8) (Signalosome subunit 8) (COP9 homolog) (hCOP9) (JAB1-containing signalosome subunit 8)
Gene: COPS8

Interactor 2: BTBD1 (Q9H0C5)
BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A-transactivated protein 8) (HCV NS5A-transactivated protein 8)
Gene: BTBD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 209 Hs			1 482
+	Hs
		1406121 CSN8_HUMAN (1-209): 4.28e-116: 330: 100.00		BTBD2_HUMAN (40-482): 9.45e-130: 388: 82.21
+	Hs
		1235384 CSN8_HUMAN (1-209): 4.28e-116: 330: 100.00		KLH10_HUMAN (57-299): 2.5e-76: 252: 21.55
+	Hs
		1406133 CSN8_HUMAN (1-209): 4.28e-116: 330: 100.00		KLHL8_HUMAN (328-471): 4.44e-16: 82.9: 11.72
+	Hs
		1406125 CSN8_HUMAN (1-209): 4.28e-116: 330: 100.00		KLHL4_HUMAN (335-476): 1.47e-10: 65.6: 9.79
+	Hs
		1406134 CSN8_HUMAN (1-209): 4.28e-116: 330: 100.00		KLH13_HUMAN (335-458): 1.3e-10: 65.6: 7.26