HitPredict

Interactor 1: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Interactor 2: NR0B2 (Q15466)
Nuclear receptor subfamily 0 group B member 2 (Orphan nuclear receptor SHP) (Small heterodimer partner)
Gene: NR0B2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	28128295
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0010628 - positive regulation of gene expression GO:0010629 - negative regulation of gene expression
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 662 Hs			1 257
+	Hs
		141357 DDX3X_HUMAN (1-662): 0: 613: 100.00		HNF4A_HUMAN (14-256): 1.42e-62: 205: 23.46
+	Hs
		141369 DDX3X_HUMAN (1-662): 0: 613: 100.00		NR2C2_HUMAN (33-256): 6.61e-59: 198: 25.89
+	Hs
		193098 DDX3Y_HUMAN (1-662): 0: 603: 91.84		ERR3_HUMAN (6-257): 1.33e-60: 199: 17.86
+	Hs
		193091 DDX3Y_HUMAN (1-662): 0: 603: 91.84		NR2C2_HUMAN (33-256): 6.61e-59: 198: 25.89
+	Mm
		542861 DDX3X_MOUSE (1-662): 0: 610: 98.64		RARA_MOUSE (48-254): 9.3e-53: 179: 17.39
+	Hs
		141324 DDX3X_HUMAN (1-662): 0: 613: 100.00		NR4A1_HUMAN (6-256): 4.46e-50: 174: 18.46
+	Hs
		608495 DDX5_HUMAN (87-659): 6.51e-158: 470: 35.36		NR2C2_HUMAN (33-256): 6.61e-59: 198: 25.89
+	Hs
		879325 DDX17_HUMAN (117-657): 5.35e-152: 458: 35.61		NR2C2_HUMAN (33-256): 6.61e-59: 198: 25.89
+	Mm
		542869 Q8BTS0_MOUSE (90-659): 5.54e-158: 470: 35.54		RARA_MOUSE (48-254): 9.3e-53: 179: 17.39
+	Hs
		608801 DDX5_HUMAN (87-659): 6.51e-158: 470: 35.36		NR2E1_HUMAN (5-255): 4.45e-52: 175: 24.27
+	Hs
		608452 DDX5_HUMAN (87-659): 6.51e-158: 470: 35.36		NR4A1_HUMAN (6-256): 4.46e-50: 174: 18.46