HitPredict

Interactor 1: GNL3 (Q9BVP2)
Guanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin)
Gene: GNL3

Interactor 2: NLE1 (Q9NVX2)
Notchless protein homolog 1
Gene: NLE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 549 Hs			1 485
+	Hs
		1380132 GNL3_HUMAN (1-549): 0: 544: 100.00		FBXW7_HUMAN (1-310): 1.23e-68: 234: 22.33
+	Hs
		1117686 NOG2_HUMAN (8-492): 4.77e-113: 354: 24.80		NLE1_HUMAN (1-485): 4.91e-139: 410: 100.00
+	Hs
		965208 GNL3_HUMAN (1-549): 0: 544: 100.00		WDR5_HUMAN (2-231): 2.76e-54: 186: 19.92
+	Sc
		673577 LSG1_YEAST (70-497): 7.43e-107: 335: 17.16		NLE1_YEAST (2-314): 1.57e-79: 258: 19.61
+	Sc
		673581 NOG2_YEAST (6-404): 1.53e-105: 327: 28.22		NLE1_YEAST (2-314): 1.57e-79: 258: 19.61
+	Sc
		673567 NUG1_YEAST (7-449): 3.14e-93: 296: 27.15		NLE1_YEAST (2-314): 1.57e-79: 258: 19.61
+	Hs
		787486 GNL1_HUMAN (23-422): 1.69e-91: 294: 18.50		WDR5_HUMAN (2-231): 2.76e-54: 186: 19.92