HitPredict

Interactor 1: ACKR2 (O00590)
Atypical chemokine receptor 2 (C-C chemokine receptor D6) (Chemokine receptor CCR-10) (Chemokine receptor CCR-9) (Chemokine-binding protein 2) (Chemokine-binding protein D6)
Gene: ACKR2

Interactor 2: CCL14 (Q16627)
C-C motif chemokine 14 (Chemokine CC-1/CC-3) (HCC-1/HCC-3) (HCC-1(1-74)) (NCC-2) (Small-inducible cytokine A14) [Cleaved into: HCC-1(3-74); HCC-1(4-74); HCC-1(9-74)]
Gene: CCL14

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	9405404
Identification Methods	pull down, competition binding
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006954 - inflammatory response GO:0060326 - cell chemotaxis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 384 Hs			1 93
+	Hs
		906961 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CCL14_HUMAN (1-93): 1.21e-39: 128: 100.00
+	Hs
		598256 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CL3L1_HUMAN (1-93): 7.66e-37: 121: 45.16
+	Hs
		561029 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CCL4_HUMAN (1-93): 1.18e-35: 118: 43.01
+	Hs
		906964 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CCL13_HUMAN (1-92): 2.28e-35: 117: 36.96
+	Hs
		518820 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CCL3_HUMAN (1-93): 4.9e-34: 113: 45.16
+	Hs
		906959 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CCL7_HUMAN (18-92): 2.69e-29: 101: 30.26
+	Hs
		906958 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CCL18_HUMAN (1-93): 3.2e-28: 99.3: 40.86
+	Hs
		906962 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CCL15_HUMAN (1-91): 5.66e-28: 99.3: 32.73
+	Hs
		562840 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CCL2_HUMAN (17-92): 2.15e-27: 97.4: 28.57
+	Hs
		562882 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CCL5_HUMAN (1-93): 8.66e-27: 95.4: 36.56
+	Hs
		907075 CCR8_HUMAN (13-361): 2.73e-97: 295: 33.24		CCL18_HUMAN (1-93): 3.2e-28: 99.3: 40.86
+	Hs
		906842 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CCL11_HUMAN (21-92): 2.64e-25: 92: 31.51
+	Hs
		906965 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CCL26_HUMAN (25-91): 4.15e-25: 91.6: 40.30
+	Hs
		124865 CCR3_HUMAN (20-360): 2.6e-99: 300: 36.71		CCL24_HUMAN (13-91): 1.03e-24: 91.2: 30.00
+	Hs
		907077 CCR8_HUMAN (13-361): 2.73e-97: 295: 33.24		CCL17_HUMAN (5-91): 1.29e-26: 95.1: 30.34
+	Hs
		648028 CCR8_HUMAN (13-361): 2.73e-97: 295: 33.24		CCL1_HUMAN (1-91): 2.04e-25: 92.4: 31.87
+	Hs
		518813 CXCR5_HUMAN (25-354): 1.96e-88: 273: 31.11		CCL3_HUMAN (1-93): 4.9e-34: 113: 45.16
+	Hs
		191478 CCR8_HUMAN (13-361): 2.73e-97: 295: 33.24		CCL16_HUMAN (1-89): 6.83e-24: 89.3: 39.56
+	Hs
		191475 CXCR5_HUMAN (25-354): 1.96e-88: 273: 31.11		CCL16_HUMAN (1-89): 6.83e-24: 89.3: 39.56
+	Hs
		855285 XCR1_HUMAN (11-342): 2.15e-90: 277: 34.94		XCL1_HUMAN (8-92): 6.45e-21: 81.2: 30.23