Protein: CCL2
C-C motif chemokine 2 (HC11) (Monocyte chemoattractant protein 1) (Monocyte chemotactic and activating factor) (MCAF) (Monocyte chemotactic protein 1) (MCP-1) (Monocyte secretory protein JE) (Small-inducible cytokine A2)

Gene: CCL2
Organism: Homo sapiens
Interactions: 46
UniProt ID: P13500

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0002548 - monocyte chemotaxis
GO:0004672 - protein kinase activity
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

562836

CCR2
C-C chemokine receptor type 2

14

20

Small-scale

0.976

High

562826

CCL2
C-C motif chemokine 2

3

18

Small-scale

0.866

High

562844

CCL8
C-C motif chemokine 8

2

19

Small-scale

0.802

High

562839

CCL11
Eotaxin

2

18

Small-scale

0.789

High

562853

CCL13
C-C motif chemokine 13

2

18

Small-scale

0.768

High

562828

CSPG2
Versican core protein

1

10

Small-scale

0.724

High

562840

CCR3
C-C chemokine receptor type 3

1

20

Small-scale

0.724

High

390356

PLF4
Platelet factor 4

1

20

High-throughput

0.716

High

562827

CCL5
C-C motif chemokine 5

1

18

High-throughput

0.716

High

518754

IL8
Interleukin-8

1

20

High-throughput

0.692

High

562847

CXCL9
C-X-C motif chemokine 9

1

20

High-throughput

0.692

High

562850

CCL15
C-C motif chemokine 15

1

19

High-throughput

0.692

High

562852

CC4L
C-C motif chemokine 4-like

1

19

High-throughput

0.692

High

562857

CCL26
C-C motif chemokine 26

1

19

High-throughput

0.692

High

562831

CCR1
C-C chemokine receptor type 1

1

20

Small-scale

0.665

High

562841

CCR5
C-C chemokine receptor type 5

1

20

Small-scale

0.665

High

562855

ACKR4
Atypical chemokine receptor 4

1

20

Small-scale

0.665

High

231413

CXL13
C-X-C motif chemokine 13

1

1

High-throughput

0.647

High

562856

XCL2
Cytokine SCM-1 beta

1

19

High-throughput

0.647

High

562837

STAT1
Signal transducer and activator of transcription 1-alpha/beta

3

5

Small-scale

0.640

High

141813

ACKR2
Atypical chemokine receptor 2

1

20

Small-scale

0.618

High

562849

ACKR1
Atypical chemokine receptor 1

2

20

Small-scale

0.595

High

562843

RNF4
E3 ubiquitin-protein ligase RNF4

2

1

High-throughput

0.553

High

562845

TSG6
Tumor necrosis factor-inducible gene 6 protein

1

15

Small-scale

0.536

High

562851

CXL17
C-X-C motif chemokine 17

1

10

High-throughput

0.536

High

562846

TF65
Transcription factor p65

1

20

Small-scale

0.515

High

562834

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

4

Small-scale

0.501

High

562829

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

20

Small-scale

0.479

High

562842

STAT2
Signal transducer and activator of transcription 2

1

5

Small-scale

0.479

High

471971

MET
Hepatocyte growth factor receptor

1

3

Small-scale

0.445

High

557054

SRC
Proto-oncogene tyrosine-protein kinase Src

1

2

Small-scale

0.445

High

562835

MMP12
Macrophage metalloelastase

1

5

Small-scale

0.445

High

183906

S22A2
Solute carrier family 22 member 2

1

1

Small-scale

0.439

High

184002

S22A1
Solute carrier family 22 member 1

1

1

Small-scale

0.439

High

562833

MOT8
Monocarboxylate transporter 8

1

2

High-throughput

0.439

High

217307

PROM1
Prominin-1

1

0

Small-scale

0.438

High

231441

ORC4
Origin recognition complex subunit 4

1

1

Small-scale

0.437

High

562830

MCM3
DNA replication licensing factor MCM3

1

2

Small-scale

0.437

High

562832

MCM7
DNA replication licensing factor MCM7

1

1

Small-scale

0.437

High

562838

MCM2
DNA replication licensing factor MCM2

1

2

Small-scale

0.437

High

562854

CDC6
Cell division control protein 6 homolog

1

1

Small-scale

0.437

High

562858

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.316

High

281171

CDC45
Cell division control protein 45 homolog

1

0

Small-scale

0.249

Low

550816

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.249

Low

562848

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025