HitPredict

Interactor 1: XCR1 (P46094)
Chemokine XC receptor 1 (G-protein coupled receptor 5) (Lymphotactin receptor) (XC chemokine receptor 1)
Gene: XCR1

Interactor 2: XCL1 (P47992)
Lymphotactin (ATAC) (C motif chemokine 1) (Cytokine SCM-1) (Lymphotaxin) (SCM-1-alpha) (Small-inducible cytokine C1) (XC chemokine ligand 1)
Gene: XCL1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9632725
Identification Methods	saturation binding
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006954 - inflammatory response GO:0051209 - release of sequestered calcium ion into cytosol GO:0060326 - cell chemotaxis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 333 Hs			1 114
+	Hs
		906964 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CCL13_HUMAN (2-92): 9e-33: 112: 25.81
+	Hs
		124865 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CCL24_HUMAN (3-98): 1.92e-28: 101: 24.24
+	Hs
		598256 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CL3L1_HUMAN (5-85): 1.41e-28: 101: 31.33
+	Hs
		906959 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CCL7_HUMAN (14-92): 9.45e-29: 101: 25.61
+	Hs
		561029 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CCL4_HUMAN (1-85): 5.5e-27: 97: 31.03
+	Hs
		562840 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CCL2_HUMAN (13-92): 1.14e-26: 96.2: 24.10
+	Hs
		906842 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CCL11_HUMAN (14-93): 2.74e-26: 95.5: 30.12
+	Hs
		518820 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CCL3_HUMAN (1-85): 7.41e-26: 94.3: 27.59
+	Hs
		906961 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CCL14_HUMAN (1-87): 2.38e-24: 90.4: 28.09
+	Hs
		190736 CCR9_HUMAN (23-307): 7.97e-85: 262: 26.17		CCL25_HUMAN (4-89): 6.02e-20: 80.8: 19.15
+	Hs
		906958 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CCL18_HUMAN (3-88): 2.51e-23: 87.7: 26.14
+	Hs
		648028 CCR8_HUMAN (1-307): 8.79e-81: 251: 35.00		CCL1_HUMAN (3-92): 7.95e-25: 91.6: 25.00
+	Hs
		141810 ACKR2_HUMAN (2-311): 2.68e-79: 248: 33.23		CCL3_HUMAN (1-85): 7.41e-26: 94.3: 27.59
+	Hs
		562882 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CCL5_HUMAN (11-86): 2.35e-22: 85.1: 26.92
+	Hs
		907075 CCR8_HUMAN (1-307): 8.79e-81: 251: 35.00		CCL18_HUMAN (3-88): 2.51e-23: 87.7: 26.14
+	Hs
		907077 CCR8_HUMAN (1-307): 8.79e-81: 251: 35.00		CCL17_HUMAN (1-85): 1.24e-21: 83.5: 24.14
+	Hs
		906962 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CCL15_HUMAN (28-85): 8.43e-20: 79.3: 36.67
+	Hs
		906965 CCR3_HUMAN (9-315): 2.78e-82: 255: 31.88		CCL26_HUMAN (24-89): 4.62e-20: 79.3: 32.35
+	Hs
		191478 CCR8_HUMAN (1-307): 8.79e-81: 251: 35.00		CCL16_HUMAN (22-83): 1.96e-20: 81.2: 25.40
+	Mm
		205653 CCR9_MOUSE (23-307): 3.36e-84: 260: 25.84		CCL25_MOUSE (4-87): 1.66e-09: 53.5: 16.48