HitPredict

Interactor 1: SMC5 (O13710)
Structural maintenance of chromosomes protein 5 (DNA repair protein spr18) (SMC partner of rad18)
Gene: SMC5

Interactor 2: NSE1 (Q53EK2)
Non-structural maintenance of chromosomes element 1 (Non-SMC element 1) (EC 2.3.2.27)
Gene: NSE1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	16478984, 12966087, 15331764
Identification Methods	affinity chromatography technology, pull down, molecular sieving, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0005634 - nucleus GO:0030915 - Smc5-Smc6 complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1076 Sp			1 232
+	Hs
		1221596 SMC5_HUMAN (6-1076): 2.87e-94: 326: 22.84		NSE1_HUMAN (5-223): 7.52e-96: 282: 28.76
+	Sp
		864194 SMC6_SCHPO (18-1032): 1.58e-62: 234: 15.29		NSE1_SCHPO (1-232): 5.85e-115: 329: 100.00
+	Hs
		1261003 SMC6_HUMAN (13-1044): 8.44e-69: 253: 15.89		NSE1_HUMAN (5-223): 7.52e-96: 282: 28.76