HitPredict

Interactor 1: EPN3 (Q9H201)
Epsin-3 (EPS-15-interacting protein 3)
Gene: EPN3

Interactor 2: KCTD3 (Q9Y597)
BTB/POZ domain-containing protein KCTD3 (Renal carcinoma antigen NY-REN-45)
Gene: KCTD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 632 Hs			1 815
+	Hs
		1348688 EPN3_HUMAN (1-632): 1.28e-92: 300: 100.00		SHKB1_HUMAN (14-661): 0: 1006: 65.46
+	Hs
		1431382 EPN3_HUMAN (1-632): 1.28e-92: 300: 100.00		BACD3_HUMAN (12-150): 1.79e-37: 144: 26.95
+	Hs
		1117921 EPN3_HUMAN (1-632): 1.28e-92: 300: 100.00		BACD2_HUMAN (2-149): 7.76e-35: 137: 26.32
+	Hs
		329487 EPN2_HUMAN (1-632): 4.98e-66: 230: 33.54		BACD3_HUMAN (12-150): 1.79e-37: 144: 26.95
+	Mm
		1296094 EPN2_MOUSE (1-632): 2.9e-67: 232: 35.75		BACD1_MOUSE (1-149): 6.33e-36: 140: 25.83
+	Mm
		92776 D3Z656_MOUSE (43-625): 6.81e-38: 153: 9.92		BACD1_MOUSE (1-149): 6.33e-36: 140: 25.83
+	Hs
		1432575 PCLO_HUMAN (132-546): 1.53e-16: 86.3: 14.01		BACD3_HUMAN (12-150): 1.79e-37: 144: 26.95
+	Mm
		1296427 PCLO_MOUSE (175-631): 9.24e-10: 64.4: 12.53		BACD1_MOUSE (1-149): 6.33e-36: 140: 25.83