HitPredict

Interactor 1: NFIB (O00712)
Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein)
Gene: NFIB

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39617063
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 420 Hs			1 1191
+	Hs
		143040 NFIB_HUMAN (1-420): 0: 702: 100.00		RC3H1_HUMAN (1-1101): 0: 764: 49.34
+	Hs
		1133452 NFIX_HUMAN (2-414): 0: 614: 61.70		RC3H1_HUMAN (1-1101): 0: 764: 49.34
+	Hs
		1087788 NFIA_HUMAN (2-414): 0: 573: 63.12		RC3H1_HUMAN (1-1101): 0: 764: 49.34
+	Hs
		143124 NFIB_HUMAN (1-420): 0: 702: 100.00		KMT2C_HUMAN (340-929): 3.43e-15: 83.5: 10.15
+	Hs
		143301 NFIB_HUMAN (1-420): 0: 702: 100.00		CHD7_HUMAN (489-1021): 3.52e-12: 73.5: 6.93
+	Hs
		142711 NFIB_HUMAN (1-420): 0: 702: 100.00		KMT2D_HUMAN (403-1074): 2.75e-11: 70.8: 9.38
+	Hs
		143157 NFIB_HUMAN (1-420): 0: 702: 100.00		CBP_HUMAN (603-1030): 1.32e-10: 68.1: 8.88
+	Hs
		1133540 NFIX_HUMAN (2-414): 0: 614: 61.70		KMT2C_HUMAN (340-929): 3.43e-15: 83.5: 10.15
+	Hs
		1133705 NFIX_HUMAN (2-414): 0: 614: 61.70		CHD7_HUMAN (489-1021): 3.52e-12: 73.5: 6.93
+	Hs
		474133 NFIC_HUMAN (1-412): 0: 603: 64.86		KMT2C_HUMAN (340-929): 3.43e-15: 83.5: 10.15
+	Hs
		161470 NFIX_HUMAN (2-414): 0: 614: 61.70		KMT2D_HUMAN (403-1074): 2.75e-11: 70.8: 9.38
+	Hs
		1133571 NFIX_HUMAN (2-414): 0: 614: 61.70		CBP_HUMAN (603-1030): 1.32e-10: 68.1: 8.88
+	Hs
		1133484 NFIX_HUMAN (2-414): 0: 614: 61.70		SRCAP_HUMAN (482-817): 8.71e-10: 65.7: 15.61
+	Hs
		474341 NFIC_HUMAN (1-412): 0: 603: 64.86		CHD7_HUMAN (489-1021): 3.52e-12: 73.5: 6.93
+	Hs
		473987 NFIC_HUMAN (1-412): 0: 603: 64.86		MDC1_HUMAN (442-806): 1.15e-11: 71.8: 12.21
+	Hs
		161396 NFIC_HUMAN (1-412): 0: 603: 64.86		KMT2D_HUMAN (403-1074): 2.75e-11: 70.8: 9.38
+	Hs
		474170 NFIC_HUMAN (1-412): 0: 603: 64.86		CBP_HUMAN (603-1030): 1.32e-10: 68.1: 8.88
+	Hs
		1087875 NFIA_HUMAN (2-414): 0: 573: 63.12		KMT2C_HUMAN (340-929): 3.43e-15: 83.5: 10.15
+	Hs
		161458 NFIA_HUMAN (2-414): 0: 573: 63.12		KMT2D_HUMAN (403-1074): 2.75e-11: 70.8: 9.38
+	Hs
		1087908 NFIA_HUMAN (2-414): 0: 573: 63.12		CBP_HUMAN (603-1030): 1.32e-10: 68.1: 8.88