HitPredict

Interactor 1: CDC48 (P25694)
Cell division control protein 48 (EC 3.6.4.6) (Cell division cycle protein 48) (Transitional endoplasmic reticulum ATPase homolog)
Gene: CDC48

Interactor 2: DFM1 (Q12743)
DER1-like family member protein 1
Gene: DFM1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.726

Property	Details
Experiments	17083136, 38448163, 29351849, 18407841, 20579315, 16179952
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex GO:0036503 - ERAD pathway
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 835 Sc			1 341
+	Hs
		875295 TERA_HUMAN (13-834): 0: 735: 66.79		DERL2_HUMAN (27-229): 5.24e-64: 204: 23.65
+	Mm
		967674 TERA_MOUSE (13-834): 0: 735: 66.79		DERL2_MOUSE (27-229): 1.39e-63: 203: 23.65
+	Sc
		636605 CDC48_YEAST (1-835): 0: 786: 100.00		DER1_YEAST (25-227): 1e-36: 133: 19.12
+	Hs
		875277 TERA_HUMAN (13-834): 0: 735: 66.79		DERL1_HUMAN (22-226): 2.17e-50: 169: 23.56
+	Dm
		1181205 TERA_DROME (16-835): 0: 736: 67.07		DERL1_DROME (21-227): 1.93e-48: 164: 21.43
+	Hs
		875147 TERA_HUMAN (13-834): 0: 735: 66.79		RHBL4_HUMAN (27-214): 3.63e-45: 158: 16.93
+	Sp
		252331 CDC48_SCHPO (14-835): 0: 701: 75.30		RBD2_SCHPO (24-292): 1.59e-44: 154: 16.30