Protein: PUR6
Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)

Gene: PUR6, ADE2
Organism: Saccharomyces cerevisiae S288C
Interactions: 37
UniProt ID: P21264

Gene Ontology (top 5):
GO:0004638 - phosphoribosylaminoimidazole carboxylase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006144 - purine nucleobase metabolic process
GO:0006189 - 'de novo' IMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636790

PUR6
Phosphoribosylaminoimidazole carboxylase

1

14

High-throughput

0.656

High

636805

SSB2
Ribosome-associated molecular chaperone SSB2

2

13

Small-scale

0.571

High

636797

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

2

High-throughput

0.541

High

636806

PXA1
Peroxisomal long-chain fatty acid import protein 2

1

1

High-throughput

0.541

High

636809

LYS5
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

1

0

High-throughput

0.518

High

631853

SRP54
Signal recognition particle subunit SRP54

1

1

High-throughput

0.494

High

636798

ANM1
Protein arginine N-methyltransferase 1

1

2

Small-scale

0.494

High

636793

SED4
Putative guanine nucleotide-exchange factor SED4

1

0

High-throughput

0.486

High

623765

MYO2
Myosin-2

1

2

Small-scale

0.481

High

392219

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.479

High

401885

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.479

High

578834

HSC82
ATP-dependent molecular chaperone HSC82

1

7

High-throughput

0.479

High

636796

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.479

High

636801

DHH1
ATP-dependent RNA helicase DHH1

1

4

High-throughput

0.479

High

636807

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

3

High-throughput

0.479

High

636813

VAM6
Vacuolar morphogenesis protein 6

1

5

High-throughput

0.479

High

533468

RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18

1

5

High-throughput

0.464

High

365557

PGK
Phosphoglycerate kinase

1

2

High-throughput

0.457

High

523044

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

525906

HSP72
Heat shock protein SSA2

1

12

High-throughput

0.445

High

543799

SSB1
Ribosome-associated molecular chaperone SSB1

1

13

High-throughput

0.445

High

636795

HSP7F
Heat shock protein homolog SSE1

1

19

High-throughput

0.445

High

636808

PFD1
Prefoldin subunit 1

1

2

High-throughput

0.445

High

636791

SPTC1
Serine palmitoyltransferase 1

1

3

High-throughput

0.437

High

636792

SIS1
Protein SIS1

1

4

High-throughput

0.437

High

636794

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

636802

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

636811

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

636814

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

636800

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.282

High

636803

EAF5
Chromatin modification-related protein EAF5

1

0

High-throughput

0.282

High

636812

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.282

High

636804

RPN3
26S proteasome regulatory subunit RPN3

1

0

High-throughput

0.269

Low

427026

FUR4
Uracil permease

1

0

High-throughput

0.238

Low

636799

YBY4
Putative uncharacterized protein YBR134W

1

0

High-throughput

0.238

Low

636810

YD271
Putative uncharacterized protein YDR271C

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025