HitPredict

Interactor 1: DDB1A (Q9M0V3)
DNA damage-binding protein 1a (UV-damaged DNA-binding protein 1a) (DDB1a)
Gene: DDB1A

Interactor 2: HTD1 (Q9ZUN8)
Protein HEAT STRESS TOLERANT DWD 1
Gene: HTD1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.713

Property	Details
Experiments	25358503
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	MMS1_N~WD40, CPSF_A~WD40
Common GO terms	GO:0016567 - protein ubiquitination GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1088 At			1 469
+	At
		198892 DDB1A_ARATH (1-1088): 0: 1321: 100.00		MSI1_ARATH (23-469): 3.63e-82: 261: 22.61
+	At
		1236577 DDB1A_ARATH (1-1088): 0: 1321: 100.00		FY_ARATH (4-341): 2.59e-43: 163: 18.87
+	Hs
		1066320 DDB1_HUMAN (3-1088): 0: 1206: 52.44		RBBP4_HUMAN (10-462): 7.75e-88: 276: 25.00
+	Hs
		1157733 DDB1_HUMAN (3-1088): 0: 1206: 52.44		RBBP7_HUMAN (13-469): 2.46e-86: 272: 23.93
+	At
		235870 DDB1B_ARATH (1-1088): 0: 1308: 91.27		FY_ARATH (4-341): 2.59e-43: 163: 18.87
+	Hs
		1157795 DDB1_HUMAN (3-1088): 0: 1206: 52.44		WDR5B_HUMAN (194-466): 2.87e-55: 189: 18.71
+	At
		198899 DDB1A_ARATH (1-1088): 0: 1321: 100.00		MSI3_ARATH (313-463): 2.29e-12: 70.4: 13.13
+	At
		198967 DDB1A_ARATH (1-1088): 0: 1321: 100.00		MSI4_ARATH (312-463): 9.8e-12: 68.9: 11.83
+	At
		879964 DDB1A_ARATH (1-1088): 0: 1321: 100.00		GBB_ARATH (199-392): 2.35e-11: 67: 28.06
+	At
		198898 DDB1B_ARATH (1-1088): 0: 1308: 91.27		MSI3_ARATH (313-463): 2.29e-12: 70.4: 13.13
+	At
		198952 DDB1B_ARATH (1-1088): 0: 1308: 91.27		MSI4_ARATH (312-463): 9.8e-12: 68.9: 11.83
+	Hs
		964975 DDB1_HUMAN (3-1088): 0: 1206: 52.44		WDR5_HUMAN (23-297): 2.2e-42: 154: 13.86
+	Hs
		1157912 DDB1_HUMAN (3-1088): 0: 1206: 52.44		TBL1R_HUMAN (2-255): 1.39e-24: 108: 9.06
+	Hs
		1157890 DDB1_HUMAN (3-1088): 0: 1206: 52.44		GRWD1_HUMAN (298-466): 3.65e-24: 106: 15.98
+	Ce
		233653 O44985_CAEEL (3-1085): 0: 951: 20.11		LIN53_CAEEL (23-468): 1.93e-81: 259: 23.50
+	Hs
		1148022 SF3B3_HUMAN (3-1085): 0: 1018: 21.15		GRWD1_HUMAN (298-466): 3.65e-24: 106: 15.98
+	Ce
		1018719 CPSF1_CAEEL (622-1087): 9.84e-101: 350: 18.80		LIN53_CAEEL (23-468): 1.93e-81: 259: 23.50
+	Hs
		1083364 CPSF1_HUMAN (632-1087): 1.84e-118: 400: 22.72		TAF5_HUMAN (119-342): 1.3e-47: 177: 20.41
+	At
		1236575 CPSF1_ARATH (31-519): 5.01e-100: 347: 17.25		FY_ARATH (4-341): 2.59e-43: 163: 18.87