HitPredict

Interactor 1: TLR8 (Q9NR97)
Toll-like receptor 8 (CD antigen CD288)
Gene: TLR8

Interactor 2: RN216 (Q9NWF9)
E3 ubiquitin-protein ligase RNF216 (EC 2.3.2.27) (RING finger protein 216) (RING-type E3 ubiquitin transferase RNF216) (Triad domain-containing protein 3) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B)
Gene: RNF216

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31385713
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1041 Hs			1 866
+	Hs
		126337 TLR4_HUMAN (37-646): 4.37e-36: 149: 15.78		RN216_HUMAN (1-866): 0: 1149: 100.00
+	Hs
		191241 TLR3_HUMAN (436-844): 1.37e-24: 113: 15.12		RN216_HUMAN (1-866): 0: 1149: 100.00
+	Hs
		1448075 TLR9_HUMAN (1-327): 1.1e-20: 100: 17.56		RN216_HUMAN (1-866): 0: 1149: 100.00
+	Hs
		252290 TLR5_HUMAN (1-158): 4.84e-09: 62.6: 16.07		RN216_HUMAN (1-866): 0: 1149: 100.00
+	Hs
		191229 TLR3_HUMAN (436-844): 1.37e-24: 113: 15.12		RNF31_HUMAN (465-748): 2.55e-55: 209: 15.89