Protein: HPF1
Histone PARylation factor 1

Gene: HPF1
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q9NWY4

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0006302 - double-strand break repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

455933

PARP1
Poly [ADP-ribose] polymerase 1

2

1

Small-scale

0.812

High

1347560

PARP2
Poly [ADP-ribose] polymerase 2

2

1

Small-scale

0.812

High

1086332

H31T
Histone H3.1t

2

2

Small-scale

0.595

High

559266

H15
Histone H1.5

2

0

Small-scale

0.577

High

408690

KPCB
Protein kinase C beta type

2

0

High-throughput

0.547

High

980999

EMX2
Homeobox protein EMX2

1

0

High-throughput

0.513

High

1295913

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

0

High-throughput

0.513

High

130280

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

1

Small-scale

0.501

High

398958

HMGN2
Non-histone chromosomal protein HMG-17

1

1

Small-scale

0.501

High

918730

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

Small-scale

0.501

High

935302

H31
Histone H3.1

1

2

Small-scale

0.501

High

952662

H33
Histone H3.3

1

2

Small-scale

0.501

High

396991

HMGN1
Non-histone chromosomal protein HMG-14

1

0

Small-scale

0.480

High

426745

H10
Histone H1.0

1

0

Small-scale

0.480

High

449823

HMGB1
High mobility group protein B1

1

0

Small-scale

0.480

High

565051

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

Small-scale

0.480

High

1347562

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

261022

H2AY
Core histone macro-H2A.1

1

1

Small-scale

0.479

High

1087441

H2B2E
Histone H2B type 2-E

1

1

Small-scale

0.479

High

881042

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.460

High

228879

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

824450

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

918035

H4
Histone H4

1

0

Small-scale

0.458

High

966297

TFAP4
Transcription factor AP-4

1

0

Small-scale

0.458

High

1087118

H2A2C
Histone H2A type 2-C

1

0

Small-scale

0.458

High

1347558

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

1347559

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1032280

CENPR
Centromere protein R

1

0

High-throughput

0.438

High

587724

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

High-throughput

0.426

High

816200

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.328

High

1347561

MKLN1
Muskelin

2

0

High-throughput

0.319

High

361938

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

0

High-throughput

0.279

Low

1122773

OCAD2
OCIA domain-containing protein 2

1

0

High-throughput

0.269

Low

385610

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1171976

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

886348

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024