HitPredict

Interactor 1: TMOD3 (Q9NYL9)
Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod)
Gene: TMOD3

Interactor 2: MYO5A (Q9Y4I1)
Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)
Gene: MYO5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007015 - actin filament organization
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 352 Hs			1 1855
+	Hs
		1453570 TMOD4_HUMAN (4-346): 1.34e-124: 363: 55.10		MYO5A_HUMAN (1-1855): 0: 1278: 100.00
+	Hs
		1452688 TMOD3_HUMAN (1-352): 1.8e-139: 401: 100.00		MYO5B_HUMAN (1-1855): 0: 1162: 61.59
+	Hs
		702058 TMOD1_HUMAN (3-348): 1.35e-127: 371: 62.14		MYO5B_HUMAN (1-1855): 0: 1162: 61.59
+	Hs
		1447556 TMOD3_HUMAN (1-352): 1.8e-139: 401: 100.00		MYO5C_HUMAN (1-1855): 0: 1040: 49.17
+	Hs
		702046 TMOD1_HUMAN (3-348): 1.35e-127: 371: 62.14		MYO5C_HUMAN (1-1855): 0: 1040: 49.17
+	Hs
		1447558 TMOD4_HUMAN (4-346): 1.34e-124: 363: 55.10		MYO5C_HUMAN (1-1855): 0: 1040: 49.17
+	Dm
		52492 A8JRH3_DROME (5-350): 8.27e-101: 308: 31.82		A1Z6Z9_DROME (4-1853): 0: 887: 35.04
+	Hs
		227806 TMOD1_HUMAN (3-348): 1.35e-127: 371: 62.14		MYO1B_HUMAN (66-914): 1e-151: 500: 36.28