HitPredict

Interactor 1: CUL2 (Q9SRZ0)
Cullin-2 (AtCUL1)
Gene: CUL2

Interactor 2: FBW2 (Q9ZPE4)
F-box protein FBW2 (SKP1-interacting partner 18)
Gene: FBW2

Species: Arabidopsis thaliana

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	12795696
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Cullin~F-box-like
Common GO terms	GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 742 At			1 317
+	At
		1375612 CUL1_ARATH (1-742): 0: 823: 69.27		FBW2_ARATH (1-317): 1.89e-99: 296: 100.00
+	At
		1375603 CUL1_ARATH (1-742): 0: 823: 69.27		SKI19_ARATH (3-246): 2.73e-54: 181: 30.61
+	At
		1375597 CUL1_ARATH (1-742): 0: 823: 69.27		SKP2A_ARATH (3-276): 1.28e-47: 165: 18.77
+	At
		235566 CUL1_ARATH (1-742): 0: 823: 69.27		SKP2B_ARATH (3-276): 9.14e-44: 155: 17.33
+	Hs
		1114700 CUL3_HUMAN (1-742): 0: 800: 28.65		KDM2A_HUMAN (13-281): 7.48e-41: 153: 17.56
+	Hs
		1113430 CUL3_HUMAN (1-742): 0: 800: 28.65		FXL19_HUMAN (13-249): 8.58e-37: 141: 16.87
+	Hs
		1101808 CUL4A_HUMAN (10-742): 0: 779: 32.52		SKP2_HUMAN (3-264): 8.37e-40: 146: 18.12
+	At
		1375613 CUL1_ARATH (1-742): 0: 823: 69.27		GRH1_ARATH (45-313): 4.44e-21: 95.5: 17.10
+	At
		1375608 CUL1_ARATH (1-742): 0: 823: 69.27		EBF1_ARATH (13-224): 5.56e-20: 92.4: 22.08
+	At
		1201576 CUL1_ARATH (1-742): 0: 823: 69.27		TIR1_ARATH (76-250): 6.94e-17: 83.2: 18.96
+	Hs
		1112608 CUL1_HUMAN (4-742): 0: 745: 28.91		KDM2B_HUMAN (13-270): 1.58e-43: 161: 17.04
+	Hs
		1114561 CUL3_HUMAN (1-742): 0: 800: 28.65		FXL17_HUMAN (12-256): 2.28e-21: 96.3: 14.46
+	Hs
		1101806 CUL1_HUMAN (4-742): 0: 745: 28.91		SKP2_HUMAN (3-264): 8.37e-40: 146: 18.12
+	Hs
		1112554 CUL1_HUMAN (4-742): 0: 745: 28.91		FXL19_HUMAN (13-249): 8.58e-37: 141: 16.87
+	At
		1375598 CUL1_ARATH (1-742): 0: 823: 69.27		AFB3_ARATH (29-283): 1.48e-09: 60.9: 12.38
+	Hs
		1115056 CUL4A_HUMAN (10-742): 0: 779: 32.52		FXL15_HUMAN (40-291): 3.35e-13: 70.9: 12.40
+	Hs
		1112656 CUL1_HUMAN (4-742): 0: 745: 28.91		FXL20_HUMAN (79-243): 4.5e-21: 94.7: 21.97
+	Hs
		1112711 CUL1_HUMAN (4-742): 0: 745: 28.91		FXL15_HUMAN (40-291): 3.35e-13: 70.9: 12.40
+	Hs
		1112595 CUL1_HUMAN (4-742): 0: 745: 28.91		FXL14_HUMAN (13-204): 9.1e-13: 70.1: 16.41
+	Hs
		1112598 CUL1_HUMAN (4-742): 0: 745: 28.91		FBXL6_HUMAN (106-225): 1.5e-09: 60.8: 20.51