HitPredict

Interactor 1: SPAST (Q9UBP0)
Spastin (EC 5.6.1.1) (Spastic paraplegia 4 protein)
Gene: SPAST

Interactor 2: SPAST (Q9UBP0)
Spastin (EC 5.6.1.1) (Spastic paraplegia 4 protein)
Gene: SPAST

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Vps4_C, AAA_lid_3~AAA_lid_3, AAA_lid_3~Vps4_C, Vps4_C~Vps4_C
Common GO terms GO:0000281 - mitotic cytokinesis
GO:0000922 - spindle pole
GO:0001578 - microtubule bundle formation
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 38 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 616
Hs

1 616
+ Mm
+ Sc
+ Dm
+ Hs
+ Mm
+ Ce
+ Hs
+ Sc
+ Hs
+ Hs
+ Af
+ Hs
+ Sp
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025