HitPredict

Interactor 1: THIO2 (Q9V429)
Thioredoxin-2 (DmTrx-2)
Gene: Trx2

Interactor 2: Q9W227 (Q9W227)
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)
Gene: DmelCG2852

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 106 Dm			1 205
+	Dm
		668123 THIO2_DROME (1-106): 1.89e-38: 126: 100.00		PPIA_DROME (13-190): 5.31e-93: 272: 52.78
+	Hs
		566553 PDIA4_HUMAN (3-105): 4.83e-26: 102: 22.02		PPIB_HUMAN (3-200): 9.77e-101: 291: 66.16
+	Hs
		656047 PDIA3_HUMAN (3-104): 3.22e-26: 102: 24.30		PPIB_HUMAN (3-200): 9.77e-101: 291: 66.16
+	Nc
		1274132 ERP38_NEUCR (3-105): 4.95e-28: 105: 26.61		PPIB_NEUCR (8-203): 5.43e-98: 287: 60.71
+	Dm
		1465316 PDIA6_DROME (3-94): 5.93e-27: 104: 18.09		Q9W227_DROME (1-205): 2.74e-98: 285: 100.00
+	Hs
		528229 THIO_HUMAN (1-106): 9.6e-38: 124: 50.00		PPIA_HUMAN (27-191): 5.94e-91: 265: 58.79
+	At
		760723 TRXY2_ARATH (6-106): 2.94e-35: 119: 35.29		CP18C_ARATH (29-191): 9.43e-93: 270: 54.71
+	Rn
		664561 PDIA4_RAT (3-105): 5.81e-24: 96.4: 23.85		PPIB_RAT (3-200): 2.2e-100: 291: 67.68
+	At
		1182467 TRXY2_ARATH (6-106): 2.94e-35: 119: 35.29		CP19A_ARATH (27-191): 3.12e-92: 268: 55.81
+	Hs
		717643 PDIA3_HUMAN (3-104): 3.22e-26: 102: 24.30		PPIE_HUMAN (22-189): 7.96e-90: 267: 53.57
+	Hs
		717434 PDIA3_HUMAN (3-104): 3.22e-26: 102: 24.30		PPIA_HUMAN (27-191): 5.94e-91: 265: 58.79
+	At
		760727 TRXH3_ARATH (19-93): 5.03e-17: 72: 48.00		CP20C_ARATH (10-193): 4.17e-98: 286: 60.33