HitPredict

Interactor 1: Q9VAY2 (Q9VAY2)
Heat shock protein 83 (HSP 82)
Gene: Gp93

Interactor 2: Q9VUC1 (Q9VUC1)
Hsc70Cb, isoform A (Hsc70Cb, isoform B) (Hsc70Cb, isoform C) (Hsc70Cb, isoform E) (Hsc70Cb, isoform F) (Hsc70Cb, isoform I) (LD32979p)
Gene: Hsp110

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HATPase_c_3~HSP70, HSP70~HSP90
Common GO terms	GO:0005524 - ATP binding GO:0006457 - protein folding GO:0140662 - ATP-dependent protein folding chaperone
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 787 Dm			1 804
+	Hs
		536417 ENPL_HUMAN (1-752): 0: 994: 61.38		HSP7C_HUMAN (2-657): 0: 831: 27.26
+	Hs
		461201 HS90A_HUMAN (69-786): 0: 950: 43.89		HSP74_HUMAN (1-804): 0: 864: 41.86
+	Hs
		461771 HS90A_HUMAN (69-786): 0: 950: 43.89		HS105_HUMAN (1-790): 0: 863: 41.78
+	Hs
		461200 HS90A_HUMAN (69-786): 0: 950: 43.89		HS71L_HUMAN (3-664): 0: 859: 29.85
+	Hs
		468119 HS90B_HUMAN (74-786): 0: 944: 43.41		HSP74_HUMAN (1-804): 0: 864: 41.86
+	Hs
		468656 HS90B_HUMAN (74-786): 0: 944: 43.41		HS105_HUMAN (1-790): 0: 863: 41.78
+	Hs
		461118 HS90A_HUMAN (69-786): 0: 950: 43.89		HSP76_HUMAN (3-655): 0: 832: 28.44
+	Hs
		461075 HS90A_HUMAN (69-786): 0: 950: 43.89		HSP7C_HUMAN (2-657): 0: 831: 27.26
+	Hs
		468038 HS90B_HUMAN (74-786): 0: 944: 43.41		HSP76_HUMAN (3-655): 0: 832: 28.44
+	Hs
		461309 HS90A_HUMAN (69-786): 0: 950: 43.89		HSP72_HUMAN (2-656): 0: 825: 27.90
+	Hs
		468001 HS90B_HUMAN (74-786): 0: 944: 43.41		HSP7C_HUMAN (2-657): 0: 831: 27.26
+	Mm
		547231 HS90B_MOUSE (74-786): 0: 946: 43.13		HS71B_MOUSE (2-655): 0: 827: 27.95
+	Ce
		482115 HSP90_CAEEL (68-778): 0: 904: 45.44		HSP1_CAEEL (2-657): 0: 826: 27.41
+	Sc
		579064 HSC82_YEAST (72-783): 0: 840: 46.19		HSP7F_YEAST (5-653): 9.98e-135: 417: 38.02
+	Sc
		392437 HSP82_YEAST (72-783): 0: 838: 45.79		HSP7F_YEAST (5-653): 9.98e-135: 417: 38.02
+	Sc
		579065 HSC82_YEAST (72-783): 0: 840: 46.19		HSP79_YEAST (5-653): 1.23e-129: 404: 37.25
+	Sc
		392438 HSP82_YEAST (72-783): 0: 838: 45.79		HSP79_YEAST (5-653): 1.23e-129: 404: 37.25
+	Sc
		578860 HSC82_YEAST (72-783): 0: 840: 46.19		HSP74_YEAST (4-650): 3.06e-80: 272: 30.53
+	Sc
		392239 HSP82_YEAST (72-783): 0: 838: 45.79		HSP74_YEAST (4-650): 3.06e-80: 272: 30.53