Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: HSP74 (P22202)
Heat shock protein SSA4
Gene: SSA4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 31399574, 37295430, 37968396
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c_3~HSP70, HSP70~HSP90
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006457 - protein folding
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 705
Sc

1 642
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ca
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Gg
+ Ce
+ Gg
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025