Interactor 1: Q9VFE9 (Q9VFE9)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2
Gene: Dph2
Interactor 2: Q9VTM2 (Q9VTM2)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)
Gene: Dph1
Species: Drosophila melanogaster
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.83 | 1.00 | 0.914 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 37061542, 14605208, 22036573, unassigned2874, 38944040 |
| Identification Methods | two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Diphthamide_syn~Diphthamide_syn |
| Common GO terms | GO:0005737 - cytoplasm GO:0017183 - protein histidyl modification to diphthamide GO:0046872 - metal ion binding GO:0051536 - iron-sulfur cluster binding GO:0090560 - 2-(3-amino-3-carboxypropyl)histidine synthase activity and 1 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
