HitPredict

Interactor 1: BIN1 (O08539)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Bridging integrator 1) (SH3 domain-containing protein 9)
Gene: BIN1

Interactor 2: DYN1 (P39053)
Dynamin-1 (EC 3.6.5.5) (Dynamin) (Dynamin I)
Gene: Dnm1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23640057
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005874 - microtubule GO:0048488 - synaptic vesicle endocytosis GO:0098793 - presynapse GO:0098978 - glutamatergic synapse
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 588 Mm			1 867
+	Rn
		148402 BIN1_RAT (1-588): 4.03e-169: 495: 99.15		DYN1_RAT (1-845): 0: 1042: 98.34
+	Hs
		138481 BIN1_HUMAN (1-587): 5.5e-159: 469: 94.44		DYN1_HUMAN (1-845): 0: 1050: 99.65
+	Mm
		147426 BIN1_MOUSE (1-588): 8.65e-171: 499: 100.00		DYN3_MOUSE (1-839): 0: 991: 78.96
+	Mm
		147412 BIN1_MOUSE (1-588): 8.65e-171: 499: 100.00		DYN2_MOUSE (1-845): 0: 985: 78.28
+	Hs
		138464 BIN1_HUMAN (1-587): 5.5e-159: 469: 94.44		DYN2_HUMAN (1-845): 0: 983: 77.93
+	Mm
		810531 AMPH_MOUSE (9-574): 9.99e-98: 314: 43.12		DYN1_MOUSE (1-867): 0: 1086: 100.00
+	Rn
		148388 AMPH_RAT (9-547): 3.27e-97: 312: 45.04		DYN1_RAT (1-845): 0: 1042: 98.34
+	Hs
		1050693 DNMBP_HUMAN (17-584): 3.23e-77: 268: 14.14		DYN1_HUMAN (1-845): 0: 1050: 99.65
+	Mm
		1274568 AMPH_MOUSE (9-574): 9.99e-98: 314: 43.12		DYN3_MOUSE (1-839): 0: 991: 78.96
+	Mm
		810550 AMPH_MOUSE (9-574): 9.99e-98: 314: 43.12		DYN2_MOUSE (1-845): 0: 985: 78.28
+	Rn
		148389 AMPH_RAT (9-547): 3.27e-97: 312: 45.04		DYN2_RAT (1-845): 0: 984: 78.16
+	Hs
		896800 DNMBP_HUMAN (17-584): 3.23e-77: 268: 14.14		DYN2_HUMAN (1-845): 0: 983: 77.93
+	Hs
		1251281 DNMBP_HUMAN (17-584): 3.23e-77: 268: 14.14		DYN3_HUMAN (1-839): 0: 978: 78.64
+	Hs
		1050729 CABIN_HUMAN (266-535): 3.28e-25: 113: 13.50		DYN1_HUMAN (1-845): 0: 1050: 99.65
+	Hs
		883038 AMPH_HUMAN (84-588): 6.68e-22: 102: 18.84		DYN1_HUMAN (1-845): 0: 1050: 99.65
+	Hs
		883030 AMPH_HUMAN (84-588): 6.68e-22: 102: 18.84		DYN2_HUMAN (1-845): 0: 983: 77.93
+	Hs
		883070 AMPH_HUMAN (84-588): 6.68e-22: 102: 18.84		DYN3_HUMAN (1-839): 0: 978: 78.64
+	Sc
		639018 RV167_YEAST (16-442): 3.9e-55: 195: 13.59		VPS1_YEAST (7-745): 0: 671: 35.92