HitPredict

Interactor 1: AMPH (P49418)
Amphiphysin
Gene: AMPH

Interactor 2: DYN1 (Q05193)
Dynamin-1 (EC 3.6.5.5) (Dynamin) (Dynamin I)
Gene: DNM1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.757

Property	Details
Experiments	9341169, 9348539, 9280305, 9148966, 29357276, 11877424, 15834155, 17244534, 10542231, unassigned3799
Identification Methods	pull down, affinity chromatography technology, peptide array, surface plasmon resonance, anti tag coimmunoprecipitation, enzyme linked immunosorbent assay
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 695 Hs			1 864
+	Mm
		810531 AMPH_MOUSE (1-695): 1.29e-123: 385: 82.90		DYN1_MOUSE (1-845): 0: 1081: 99.65
+	Rn
		148388 AMPH_RAT (1-695): 1.17e-119: 374: 84.75		DYN1_RAT (1-864): 0: 1081: 98.03
+	Hs
		883030 AMPH_HUMAN (1-695): 2.85e-138: 423: 100.00		DYN2_HUMAN (1-860): 0: 1021: 78.91
+	Hs
		883070 AMPH_HUMAN (1-695): 2.85e-138: 423: 100.00		DYN3_HUMAN (1-860): 0: 998: 78.12
+	Mm
		810550 AMPH_MOUSE (1-695): 1.29e-123: 385: 82.90		DYN2_MOUSE (1-860): 0: 1022: 79.13
+	Mm
		1274568 AMPH_MOUSE (1-695): 1.29e-123: 385: 82.90		DYN3_MOUSE (1-860): 0: 1012: 78.55
+	Rn
		148389 AMPH_RAT (1-695): 1.17e-119: 374: 84.75		DYN2_RAT (1-860): 0: 1021: 79.02
+	Hs
		1050693 DNMBP_HUMAN (12-536): 3.52e-59: 218: 18.97		DYN1_HUMAN (1-864): 0: 1087: 100.00
+	Hs
		896800 DNMBP_HUMAN (12-536): 3.52e-59: 218: 18.97		DYN2_HUMAN (1-860): 0: 1021: 78.91
+	Hs
		138481 BIN1_HUMAN (375-694): 2.11e-33: 138: 22.81		DYN1_HUMAN (1-864): 0: 1087: 100.00
+	Mm
		147411 BIN1_MOUSE (369-695): 5.09e-35: 142: 22.94		DYN1_MOUSE (1-845): 0: 1081: 99.65
+	Rn
		148402 BIN1_RAT (369-695): 2.3e-34: 140: 22.94		DYN1_RAT (1-864): 0: 1081: 98.03
+	Hs
		1251281 DNMBP_HUMAN (12-536): 3.52e-59: 218: 18.97		DYN3_HUMAN (1-860): 0: 998: 78.12
+	Mm
		147412 BIN1_MOUSE (369-695): 5.09e-35: 142: 22.94		DYN2_MOUSE (1-860): 0: 1022: 79.13
+	Hs
		1050729 CABIN_HUMAN (291-589): 2.26e-12: 72.8: 12.87		DYN1_HUMAN (1-864): 0: 1087: 100.00
+	Hs
		138464 BIN1_HUMAN (375-694): 2.11e-33: 138: 22.81		DYN2_HUMAN (1-860): 0: 1021: 78.91
+	Mm
		147426 BIN1_MOUSE (369-695): 5.09e-35: 142: 22.94		DYN3_MOUSE (1-860): 0: 1012: 78.55
+	Ce
		110886 G5ECK4_CAEEL (12-625): 7.44e-33: 138: 15.04		DYN1_CAEEL (3-805): 0: 916: 64.18
+	Sc
		639018 RV167_YEAST (11-401): 2.15e-44: 168: 15.53		VPS1_YEAST (7-623): 0: 620: 38.38