HitPredict

Interactor 1: GOSR2 (Q9VRL2)
Probable Golgi SNAP receptor complex member 2
Gene: Membrin

Interactor 2: Q9VVX6 (Q9VVX6)
BET1 homolog (Golgi vesicular membrane-trafficking protein p18)
Gene: Bet1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~V-SNARE_C
Common GO terms	GO:0000139 - Golgi membrane GO:0005484 - SNAP receptor activity GO:0015031 - protein transport GO:0016192 - vesicle-mediated transport GO:0031201 - SNARE complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 216 Dm			1 117
+	Rn
		204396 GOSR2_RAT (1-214): 5.14e-62: 194: 42.99		BET1_RAT (7-117): 1.19e-36: 122: 36.94
+	Hs
		160223 GOSR2_HUMAN (1-214): 4.28e-60: 189: 41.12		BET1_HUMAN (10-117): 1.08e-36: 122: 39.82
+	At
		1375200 VTI12_ARATH (1-213): 6.41e-61: 191: 16.51		SYP61_ARATH (2-113): 1.49e-28: 105: 16.52
+	Hs
		180009 VTI1A_HUMAN (1-213): 1.44e-49: 162: 17.05		BET1_HUMAN (10-117): 1.08e-36: 122: 39.82
+	Hs
		160340 GOSR2_HUMAN (1-214): 4.28e-60: 189: 41.12		BET1L_HUMAN (20-114): 3.44e-24: 90.5: 31.25
+	Dm
		1487520 Q9W0N6_DROME (1-207): 4.15e-45: 151: 18.01		Q9VVX6_DROME (1-117): 3.51e-37: 123: 100.00
+	Hs
		160226 GOSR2_HUMAN (1-214): 4.28e-60: 189: 41.12		STX6_HUMAN (8-100): 1.41e-19: 82.4: 22.58
+	Hs
		180094 VTI1B_HUMAN (1-193): 4.37e-43: 146: 14.87		BET1_HUMAN (10-117): 1.08e-36: 122: 39.82
+	At
		1318926 MEM12_ARATH (1-215): 1.68e-57: 182: 26.85		BETL2_ARATH (7-96): 5.63e-18: 75.5: 15.63
+	Mm
		313465 VTI1A_MOUSE (1-215): 2.6e-53: 172: 17.35		STX6_MOUSE (8-100): 5.95e-20: 83.2: 22.58
+	Hs
		249887 VTI1A_HUMAN (1-213): 1.44e-49: 162: 17.05		STX10_HUMAN (18-100): 5.6e-21: 85.9: 20.48
+	Hs
		226165 VTI1A_HUMAN (1-213): 1.44e-49: 162: 17.05		STX6_HUMAN (8-100): 1.41e-19: 82.4: 22.58
+	Rn
		1224613 VTI1A_RAT (1-215): 8.81e-48: 158: 16.37		STX6_RAT (8-101): 3e-20: 83.9: 22.34
+	Mm
		1362332 Q91XH6_MOUSE (2-213): 7.67e-48: 158: 16.28		STX6_MOUSE (8-100): 5.95e-20: 83.2: 22.58
+	Hs
		1217087 VTI1A_HUMAN (1-213): 1.44e-49: 162: 17.05		Q5U8S2_HUMAN (18-92): 2.5e-17: 76.2: 20.00
+	Hs
		249908 VTI1B_HUMAN (1-193): 4.37e-43: 146: 14.87		STX10_HUMAN (18-100): 5.6e-21: 85.9: 20.48
+	Hs
		226247 VTI1B_HUMAN (1-193): 4.37e-43: 146: 14.87		STX6_HUMAN (8-100): 1.41e-19: 82.4: 22.58