HitPredict

Interactor 1: GOSR2 (Q9VRL2)
Probable Golgi SNAP receptor complex member 2
Gene: Membrin

Interactor 2: Q9W3M8 (Q9W3M8)
LD34211p (YKT6 v-SNARE (EC 2.3.1.225))
Gene: Ykt6

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Synaptobrevin~V-SNARE_C
Common GO terms	GO:0000139 - Golgi membrane GO:0005484 - SNAP receptor activity GO:0005794 - Golgi apparatus GO:0016192 - vesicle-mediated transport GO:0031201 - SNARE complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 216 Dm			1 199
+	Rn
		204395 GOSR2_RAT (1-214): 5.14e-62: 194: 42.99		SC22B_RAT (1-198): 1.08e-57: 182: 18.72
+	Hs
		160229 GOSR2_HUMAN (1-214): 4.28e-60: 189: 41.12		SC22B_HUMAN (1-198): 1.08e-57: 182: 18.72
+	Dm
		1489423 Q9W0N6_DROME (1-207): 4.15e-45: 151: 18.01		Q9W3M8_DROME (1-199): 1.12e-72: 219: 100.00
+	At
		235609 VTI11_ARATH (1-195): 4.7e-57: 181: 15.08		VA711_ARATH (29-198): 1.63e-58: 184: 20.33
+	Dm
		305592 GOSR2_DROME (1-216): 9.81e-58: 183: 100.00		O77434_DROME (1-198): 6.49e-55: 175: 17.91
+	Dm
		121827 GOSR2_DROME (1-216): 9.81e-58: 183: 100.00		M9PGI6_DROME (1-198): 2e-54: 174: 17.73
+	Dm
		1263469 GOSR2_DROME (1-216): 9.81e-58: 183: 100.00		Q7JYX5_DROME (29-198): 1.66e-54: 174: 22.10
+	Hs
		280297 VTI1A_HUMAN (1-213): 1.44e-49: 162: 17.05		SC22B_HUMAN (1-198): 1.08e-57: 182: 18.72
+	Sc
		779512 VTI1_YEAST (3-197): 3.65e-38: 133: 18.09		YKT6_YEAST (2-198): 9.31e-67: 204: 44.22
+	Mm
		312202 VTI1B_MOUSE (2-213): 9.32e-48: 158: 15.81		VAMP7_MOUSE (29-196): 1.07e-55: 177: 18.99
+	Hs
		280365 VTI1B_HUMAN (1-193): 4.37e-43: 146: 14.87		SC22B_HUMAN (1-198): 1.08e-57: 182: 18.72
+	Dm
		121835 Q9W0N6_DROME (1-207): 4.15e-45: 151: 18.01		M9PGI6_DROME (1-198): 2e-54: 174: 17.73
+	Dm
		1263478 Q9W0N6_DROME (1-207): 4.15e-45: 151: 18.01		Q7JYX5_DROME (29-198): 1.66e-54: 174: 22.10
+	Hs
		908061 VTI1B_HUMAN (1-193): 4.37e-43: 146: 14.87		VAMP7_HUMAN (29-196): 1.65e-55: 177: 19.55
+	Dm
		84894 B7Z0M0_DROME (111-193): 1.17e-14: 69.4: 14.46		Q9W3M8_DROME (1-199): 1.12e-72: 219: 100.00
+	Sc
		646266 VTI1_YEAST (3-197): 3.65e-38: 133: 18.09		SEC22_YEAST (1-193): 8.3e-46: 152: 24.12
+	Dm
		84840 B7Z0M0_DROME (111-193): 1.17e-14: 69.4: 14.46		O77434_DROME (1-198): 6.49e-55: 175: 17.91
+	Dm
		84855 B7Z0M0_DROME (111-193): 1.17e-14: 69.4: 14.46		Q7JYX5_DROME (29-198): 1.66e-54: 174: 22.10
+	Sc
		1046463 VTI1_YEAST (3-197): 3.65e-38: 133: 18.09		NYV1_YEAST (58-198): 2.83e-28: 108: 12.26