Protein: YKT6
Synaptobrevin homolog YKT6 (EC 2.3.1.-)

Gene: YKT6
Organism: Saccharomyces cerevisiae S288C
Interactions: 119
UniProt ID: P36015

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000324 - fungal-type vacuole
GO:0000421 - autophagosome membrane
GO:0005484 - SNAP receptor activity
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

779512

VTI1
t-SNARE VTI1

11

18

Small-scale

0.978

High

779522

VAM3
Syntaxin VAM3

11

20

Small-scale

0.975

High

779506

SED5
Integral membrane protein SED5

10

20

Small-scale

0.972

High

779469

GOSR1
Golgi SNAP receptor complex member 1

5

20

Small-scale

0.920

High

743450

SEC17
Alpha-soluble NSF attachment protein

5

19

Small-scale

0.919

High

646184

SLY1
Protein SLY1

5

12

Small-scale

0.912

High

746125

PEP12
Syntaxin PEP12

4

20

Small-scale

0.899

High

635030

VPS33
Vacuolar protein sorting-associated protein 33

3

13

Small-scale

0.873

High

746423

SSO1
Protein SSO1

3

20

Small-scale

0.845

High

646230

SEC22
Protein transport protein SEC22

3

8

Small-scale

0.840

High

779477

SSO2
Protein SSO2

3

20

Small-scale

0.833

High

779523

NYV1
Vacuolar v-SNARE NYV1

2

15

Small-scale

0.802

High

673630

BOS1
Protein transport protein BOS1

2

1

Small-scale

0.768

High

779470

VPS45
Vacuolar protein sorting-associated protein 45

2

13

High-throughput

0.759

High

779463

YKT6
Synaptobrevin homolog YKT6

2

8

Small-scale

0.755

High

779517

TLG2
t-SNARE affecting a late Golgi compartment protein 2

2

20

Small-scale

0.737

High

748210

VAM7
Vacuolar morphogenesis protein 7

4

9

Small-scale

0.699

High

652917

BET1
Protein transport protein BET1

4

17

Small-scale

0.686

High

779471

VPS41
Vacuolar protein sorting-associated protein 41

3

1

Small-scale

0.667

High

779527

SEC39
Protein transport protein SEC39

3

1

Small-scale

0.667

High

779493

SFT1
Protein transport protein SFT1

3

1

Small-scale

0.651

High

779491

UFE1
Syntaxin UFE1

3

1

Small-scale

0.646

High

628315

PGTB2
Geranylgeranyl transferase type-2 subunit beta

1

2

Small-scale

0.618

High

701688

URA7
CTP synthase 1

3

0

High-throughput

0.616

High

779498

USE1
Protein transport protein USE1

2

1

Small-scale

0.611

High

779478

VAC8
Vacuolar protein 8

2

1

Small-scale

0.602

High

779497

ATG1
Serine/threonine-protein kinase ATG1

2

1

Small-scale

0.602

High

779510

TLG1
t-SNARE affecting a late Golgi compartment protein 1

2

20

Small-scale

0.595

High

392543

HSP82
ATP-dependent molecular chaperone HSP82

2

1

High-throughput

0.584

High

536105

ARF1
ADP-ribosylation factor 1

2

4

Small-scale

0.584

High

579185

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.584

High

616414

SEC18
Vesicular-fusion protein SEC18

2

7

Small-scale

0.584

High

726928

HS104
Heat shock protein 104

2

1

High-throughput

0.584

High

705125

SEC20
Protein transport protein SEC20

2

1

Small-scale

0.571

High

779521

RIO1
Serine/threonine-protein kinase RIO1

2

0

Small-scale

0.561

High

434996

RS3
Small ribosomal subunit protein uS3

2

0

Small-scale

0.559

High

779509

VPS16
Vacuolar protein sorting-associated protein 16

1

0

Small-scale

0.537

High

779511

GCN5
Histone acetyltransferase GCN5

1

1

High-throughput

0.536

High

779476

UIP3
ULP1-interacting protein 3

1

0

High-throughput

0.518

High

779472

AKR1
Palmitoyltransferase AKR1

1

0

High-throughput

0.513

High

779501

DSL1
Protein transport protein DSL1

1

0

Small-scale

0.513

High

779490

BNI1
Protein BNI1

1

1

High-throughput

0.501

High

725993

STX8
Syntaxin-8

1

0

Small-scale

0.493

High

376290

YPT1
GTP-binding protein YPT1

1

4

Small-scale

0.479

High

518264

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.479

High

548687

RNA1
Ran GTPase-activating protein 1

1

1

High-throughput

0.479

High

639001

VPS1
Vacuolar protein sorting-associated protein 1

1

1

High-throughput

0.479

High

743328

FIMB
Fimbrin

1

1

High-throughput

0.479

High

755056

TIP20
Protein transport protein TIP20

1

1

Small-scale

0.479

High

779464

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

779465

ARL1
ADP-ribosylation factor-like protein 1

1

6

High-throughput

0.479

High

779466

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.479

High

779482

COG3
Conserved oligomeric Golgi complex subunit 3

1

1

Small-scale

0.479

High

779484

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

2

High-throughput

0.479

High

779485

SEC9
Protein transport protein SEC9

1

1

Small-scale

0.479

High

779492

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

779505

NUM1
Nuclear migration protein NUM1

1

2

High-throughput

0.479

High

779508

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

1

High-throughput

0.479

High

779513

IMB1
Importin subunit beta-1

1

3

High-throughput

0.479

High

779519

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.479

High

779520

ATG9
Autophagy-related protein 9

1

2

Small-scale

0.479

High

779530

HPH1
Protein HPH1

1

0

High-throughput

0.460

High

368158

THDH
Threonine dehydratase, mitochondrial

1

0

High-throughput

0.458

High

383628

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

410052

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

454986

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

512933

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

647082

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

661609

MPCP
Mitochondrial phosphate carrier protein

1

0

High-throughput

0.458

High

689376

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

778254

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

779468

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

779479

GEA2
ARF guanine-nucleotide exchange factor 2

1

0

High-throughput

0.458

High

779486

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

779494

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.458

High

779495

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

779500

COPZ
Coatomer subunit zeta

1

0

High-throughput

0.458

High

779507

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

779518

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

779524

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.458

High

544434

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

592171

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

631892

SRP54
Signal recognition particle subunit SRP54

1

1

High-throughput

0.445

High

779483

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

779515

VAM6
Vacuolar morphogenesis protein 6

1

3

Small-scale

0.445

High

598393

TUP1
General transcriptional corepressor TUP1

1

1

High-throughput

0.439

High

779488

MAD1
Spindle assembly checkpoint component MAD1

1

3

High-throughput

0.439

High

585700

UBC4
Ubiquitin-conjugating enzyme E2 4

1

1

High-throughput

0.437

High

706759

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

708714

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

779480

IMB4
Importin subunit beta-4

1

3

High-throughput

0.437

High

779496

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.437

High

779502

UFD2
E4 ubiquitin-protein ligase UFD2

1

1

High-throughput

0.437

High

779516

SUB2
ATP-dependent RNA helicase SUB2

1

1

High-throughput

0.437

High

779525

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.437

High

575923

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

779526

SET6
Potential protein lysine methyltransferase SET6

1

1

High-throughput

0.407

High

779529

SUS1
SAGA complex subunit SUS1

1

0

High-throughput

0.279

Low

517978

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.261

Low

779489

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

High-throughput

0.251

Low

386668

TBB
Tubulin beta chain

1

0

High-throughput

0.249

Low

705156

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

721837

XPO1
Exportin-1

1

0

High-throughput

0.249

Low

763872

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

764051

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

779467

POA1
ADP-ribose 1''-phosphate phosphatase

1

0

High-throughput

0.249

Low

779473

STM1
Suppressor protein STM1

1

0

Small-scale

0.249

Low

779474

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.249

Low

779481

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.249

Low

779487

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

779499

RBG2
Ribosome-interacting GTPase 2

1

0

High-throughput

0.249

Low

779503

ACT
Actin

1

0

Small-scale

0.249

Low

779504

H3
Histone H3

1

0

High-throughput

0.249

Low

779514

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

779528

ATG44
Mitofissin

1

0

High-throughput

0.249

Low

419695

H2A2
Histone H2A.2

1

0

High-throughput

0.232

Low

486128

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.232

Low

779475

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025