Interactor 1: SUCA (Q9WUM5)
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (EC 6.2.1.4) (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha)
Gene: Suclg1

Interactor 2: SUCB2 (Q9Z2I8)
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (G-SCS) (GTPSCS) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG)
Gene: Suclg2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-grasp_2~CoA_binding, CoA_binding~Ligase_CoA, ATP-grasp_2~Ligase_CoA, Ligase_CoA~Ligase_CoA
Common GO terms GO:0004775 - succinate-CoA ligase (ADP-forming) activity
GO:0004776 - succinate-CoA ligase (GDP-forming) activity
GO:0005739 - mitochondrion
GO:0006099 - tricarboxylic acid cycle
GO:0045244 - succinate-CoA ligase complex (GDP-forming)
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 346
Mm

1 433
+ Ss
+ Hs
+ Mm
+ Hs
+ Sc
+ Ec
+ Cj
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025