Protein: SUCB2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (G-SCS) (GTPSCS) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG)

Gene: SUCB2, SUCLG2
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q96I99

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004776 - succinate-CoA ligase (GDP-forming) activity
GO:0005524 - ATP binding
GO:0005525 - GTP binding
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921451

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

4

8

Small-scale

0.899

High

1310314

HSC20
Iron-sulfur cluster co-chaperone protein HscB

2

1

Small-scale

0.633

High

279866

CISY
Citrate synthase, mitochondrial

1

4

High-throughput

0.618

High

1141597

OZF
Zinc finger protein OZF

3

1

High-throughput

0.609

High

1394135

DJC12
DnaJ homolog subfamily C member 12

3

2

High-throughput

0.609

High

401305

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

4

High-throughput

0.584

High

1162492

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

1

High-throughput

0.584

High

372849

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.571

High

1209517

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

4

High-throughput

0.571

High

908074

GP143
G-protein coupled receptor 143

1

0

Small-scale

0.537

High

564212

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.536

High

1113996

CUL3
Cullin-3

1

5

High-throughput

0.536

High

1102520

SGCG
Gamma-sarcoglycan

1

0

High-throughput

0.518

High

365772

KAD1
Adenylate kinase isoenzyme 1

1

0

High-throughput

0.513

High

1394139

ORNT1
Mitochondrial ornithine transporter 1

1

0

High-throughput

0.513

High

1066242

DMWD
Dystrophia myotonica WD repeat-containing protein

1

3

High-throughput

0.489

High

1394128

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

1

High-throughput

0.489

High

242592

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

348662

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

High-throughput

0.479

High

471189

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

537711

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

935002

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

959228

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.479

High

1140695

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

1142632

PDK1
[Pyruvate dehydrogenase

1

1

High-throughput

0.479

High

1207104

SYAM
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

1234490

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.479

High

1394126

IMP2L
Mitochondrial inner membrane protease subunit 2

1

2

High-throughput

0.479

High

1394127

RIOK1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.479

High

1394132

ZFYV1
Zinc finger FYVE domain-containing protein 1

1

3

Small-scale

0.479

High

560052

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.458

High

653508

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.445

High

1135918

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

2

Small-scale

0.445

High

1394133

S22AB
Solute carrier family 22 member 11

1

1

High-throughput

0.445

High

1394136

S22AD
Solute carrier family 22 member 13

1

1

High-throughput

0.445

High

1394140

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

4

High-throughput

0.445

High

256952

H2B1K
Histone H2B type 1-K

1

2

High-throughput

0.437

High

845344

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

2

High-throughput

0.437

High

879365

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.437

High

981011

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.437

High

1100235

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.437

High

1155661

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.437

High

1255075

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1334777

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.437

High

1372264

H2B1H
Histone H2B type 1-H

1

2

High-throughput

0.437

High

1386320

FAF2
FAS-associated factor 2

1

2

High-throughput

0.437

High

1394129

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.437

High

1394130

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.437

High

1394131

ECT2
Protein ECT2

1

1

High-throughput

0.437

High

1394134

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

1394137

FND3A
Fibronectin type-III domain-containing protein 3A

1

2

High-throughput

0.437

High

127165

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.426

High

635906

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.426

High

848059

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

0

High-throughput

0.426

High

896435

ERF
ETS domain-containing transcription factor ERF

1

0

High-throughput

0.426

High

1291657

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.426

High

1366174

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.426

High

1394125

CPNS2
Calpain small subunit 2

1

0

High-throughput

0.426

High

1336127

GLT11
Polypeptide N-acetylgalactosaminyltransferase 11

3

0

High-throughput

0.347

High

322982

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

0

High-throughput

0.279

Low

1394138

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.279

Low

1249931

PAMR1
Inactive serine protease PAMR1

1

0

High-throughput

0.269

Low

415786

HSPB1
Heat shock protein beta-1

1

0

Small-scale

0.249

Low

716936

RL12
Large ribosomal subunit protein uL11

1

0

High-throughput

0.249

Low

1040893

MECOM
Histone-lysine N-methyltransferase MECOM

1

0

High-throughput

0.249

Low

1106658

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.249

Low

1218982

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.249

Low

1325897

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.232

Low

1389661

MFSD3
Major facilitator superfamily domain-containing protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025