Interactor 1: SUCC (P0A836)
Succinate--CoA ligase [ADP-forming] subunit beta (EC 6.2.1.5) (Succinyl-CoA synthetase subunit beta) (SCS-beta)
Gene: SUCC
Interactor 2: SUCD (P0AGE9)
Succinate--CoA ligase [ADP-forming] subunit alpha (EC 6.2.1.5) (Succinyl-CoA synthetase subunit alpha) (SCS-alpha)
Gene: SUCD
Species: Escherichia coli K-12
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.88 | 1.00 | 0.939 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29176613, 16606699, 28524877, 19402753, unassigned104, 16858726 |
| Identification Methods | affinity chromatography technology, cross-linking study, tandem affinity purification, pull down, comigration in non denaturing gel electrophoresis, blue native page |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ATP-grasp_2~CoA_binding, ATP-grasp_2~Ligase_CoA, CoA_binding~Ligase_CoA, Ligase_CoA~Ligase_CoA |
| Common GO terms | GO:0004775 - succinate-CoA ligase (ADP-forming) activity GO:0004776 - succinate-CoA ligase (GDP-forming) activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006099 - tricarboxylic acid cycle and 1 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
