HitPredict

Interactor 1: NHRF1 (O14745)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
Gene: NHERF1

Interactor 2: PLCB3 (Q01970)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3)
Gene: PLCB3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 11285285
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 358 Hs			1 1234
+	Hs
		968255 NHRF2_HUMAN (5-358): 2.98e-67: 216: 49.44		PLCB3_HUMAN (1-1234): 0: 1137: 100.00
+	Hs
		961593 NHRF2_HUMAN (5-358): 2.98e-67: 216: 49.44		PLCB2_HUMAN (13-1227): 0: 981: 43.37
+	Hs
		968271 SNX27_HUMAN (12-91): 4.35e-09: 59.7: 37.63		PLCB3_HUMAN (1-1234): 0: 1137: 100.00
+	Hs
		153948 NHRF1_HUMAN (1-358): 2.51e-82: 256: 100.00		PLCB1_HUMAN (1-1233): 0: 856: 46.43