HitPredict

Interactor 1: RASM (O14807)
Ras-related protein M-Ras (EC 3.6.5.2) (Ras-related protein R-Ras3)
Gene: MRAS

Interactor 2: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	1.00	0.653

Property	Details
Experiments	10446149
Identification Methods	coimmunoprecipitation, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DIL~Ras, PDZ~Ras, RA~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 208 Hs			1 1824
+	Mm
		140118 RASM_MOUSE (1-208): 1.28e-96: 281: 96.64		AFAD_MOUSE (1-1824): 0: 1234: 92.98
+	Hs
		876344 RRAS2_HUMAN (14-194): 8.41e-64: 197: 60.00		AFAD_HUMAN (1-1824): 0: 1279: 100.00
+	Hs
		876348 RAP1A_HUMAN (14-180): 3.95e-57: 180: 53.57		AFAD_HUMAN (1-1824): 0: 1279: 100.00
+	Hs
		894825 RAB8A_HUMAN (6-208): 8.23e-77: 231: 27.75		MYO5B_HUMAN (102-939): 4.92e-118: 416: 14.72
+	Hs
		914453 RB11A_HUMAN (4-206): 4.37e-77: 231: 27.57		MYO5B_HUMAN (102-939): 4.92e-118: 416: 14.72
+	Rn
		914521 RB11A_RAT (4-206): 4.37e-77: 231: 27.57		MYO5B_RAT (102-939): 4.23e-117: 413: 14.69
+	Ce
		1088854 RAB10_CAEEL (6-206): 2.6e-78: 234: 28.71		Q17383_CAEEL (102-968): 5.49e-105: 375: 13.83
+	Hs
		914346 RB11A_HUMAN (4-206): 4.37e-77: 231: 27.57		KI13A_HUMAN (184-691): 2.35e-70: 264: 13.74
+	Hs
		914382 RB11A_HUMAN (4-206): 4.37e-77: 231: 27.57		KI13B_HUMAN (184-691): 5.1e-66: 250: 12.64
+	Hs
		918872 RAB1A_HUMAN (1-206): 8.57e-83: 246: 30.14		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		1066669 RAB1B_HUMAN (6-206): 3.6e-81: 242: 30.05		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Ce
		1229399 RAB10_CAEEL (6-206): 2.6e-78: 234: 28.71		Q8MYQ0_CAEEL (502-968): 1.71e-60: 219: 15.24
+	Hs
		905425 RRAS2_HUMAN (14-194): 8.41e-64: 197: 60.00		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		914375 RB11A_HUMAN (4-206): 4.37e-77: 231: 27.57		GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72
+	Mm
		1143458 RAB14_MOUSE (1-204): 1.62e-79: 238: 30.73		DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51
+	Mm
		895578 RAB10_MOUSE (6-205): 1.25e-79: 238: 29.85		DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51
+	Hs
		914066 RB11A_HUMAN (4-206): 4.37e-77: 231: 27.57		SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85
+	Hs
		894813 RAB8A_HUMAN (6-208): 8.23e-77: 231: 27.75		MYO5C_HUMAN (1345-1816): 2.22e-12: 75: 9.60
+	Hs
		914383 RB11A_HUMAN (4-206): 4.37e-77: 231: 27.57		MYO5C_HUMAN (1345-1816): 2.22e-12: 75: 9.60
+	Hs
		914486 RB11A_HUMAN (4-206): 4.37e-77: 231: 27.57		MYO5A_HUMAN (1369-1800): 2.36e-11: 71.5: 10.74