HitPredict

Interactor 1: DC1I1 (O14576)
Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1)
Gene: DYNC1I1

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28718761
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 645 Hs			1 535
+	Hs
		156659 DC1I1_HUMAN (1-645): 2.52e-150: 451: 100.00		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		1104252 DC1I2_HUMAN (1-645): 2.78e-134: 409: 74.88		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		1007000 DC1I2_HUMAN (1-645): 2.78e-134: 409: 74.88		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		156591 DC1I1_HUMAN (1-645): 2.52e-150: 451: 100.00		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		156605 DC1I1_HUMAN (1-645): 2.52e-150: 451: 100.00		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		881906 DC1I2_HUMAN (1-645): 2.78e-134: 409: 74.88		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		610645 DC1I2_HUMAN (1-645): 2.78e-134: 409: 74.88		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		875943 DC1I2_HUMAN (1-645): 2.78e-134: 409: 74.88		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		1407559 DNAI2_HUMAN (158-638): 8.09e-105: 332: 20.89		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		1007265 DNAI2_HUMAN (158-638): 8.09e-105: 332: 20.89		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		882148 DNAI2_HUMAN (158-638): 8.09e-105: 332: 20.89		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		610878 DNAI2_HUMAN (158-638): 8.09e-105: 332: 20.89		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		876162 DNAI2_HUMAN (158-638): 8.09e-105: 332: 20.89		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		1407594 NLE1_HUMAN (195-605): 1.96e-84: 275: 15.79		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		1007305 NLE1_HUMAN (195-605): 1.96e-84: 275: 15.79		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		1007197 DC2I2_HUMAN (206-608): 5.91e-80: 264: 20.46		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		882085 DC2I2_HUMAN (206-608): 5.91e-80: 264: 20.46		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		876199 NLE1_HUMAN (195-605): 1.96e-84: 275: 15.79		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		610823 DC2I2_HUMAN (206-608): 5.91e-80: 264: 20.46		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		610813 FBXW7_HUMAN (4-601): 1.59e-73: 252: 12.71		TCPA_HUMAN (5-533): 0: 541: 34.30