HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (EC 3.6.1.-) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: DNAI2 (Q9GZS0)
Dynein axonemal intermediate chain 2 (Axonemal dynein intermediate chain 2)
Gene: DNAI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 605
+	Hs
		876081 TCPE_HUMAN (1-541): 0: 637: 100.00		POC1B_HUMAN (68-391): 2.56e-56: 199: 12.04
+	Hs
		876199 TCPE_HUMAN (1-541): 0: 637: 100.00		NLE1_HUMAN (294-602): 1.94e-53: 191: 11.45
+	Ce
		866358 TCPE_CAEEL (3-540): 0: 587: 68.40		LIN53_CAEEL (134-492): 5.17e-62: 212: 13.23
+	Hs
		876070 TCPE_HUMAN (1-541): 0: 637: 100.00		POC1A_HUMAN (80-345): 5.49e-40: 152: 12.41
+	Hs
		882051 TCPG_HUMAN (14-540): 0: 574: 33.15		POC1B_HUMAN (68-391): 2.56e-56: 199: 12.04
+	Hs
		876112 TCPE_HUMAN (1-541): 0: 637: 100.00		SNR40_HUMAN (394-603): 2.3e-33: 132: 12.62
+	Hs
		875904 TCPE_HUMAN (1-541): 0: 637: 100.00		GBB2_HUMAN (358-564): 1.19e-26: 113: 15.24
+	Hs
		876146 TCPE_HUMAN (1-541): 0: 637: 100.00		TBL1Y_HUMAN (392-603): 4.38e-21: 99: 12.44
+	Hs
		875898 TCPE_HUMAN (1-541): 0: 637: 100.00		WDR5_HUMAN (446-596): 1.52e-21: 98.2: 8.44
+	Hs
		845257 TCPG_HUMAN (14-540): 0: 574: 33.15		LIS1_HUMAN (360-602): 2.67e-41: 156: 14.62
+	Hs
		875943 TCPE_HUMAN (1-541): 0: 637: 100.00		DC1I2_HUMAN (266-576): 3.08e-18: 90.5: 10.62
+	Hs
		882038 TCPG_HUMAN (14-540): 0: 574: 33.15		POC1A_HUMAN (80-345): 5.49e-40: 152: 12.41
+	Hs
		156605 TCPE_HUMAN (1-541): 0: 637: 100.00		DC1I1_HUMAN (266-529): 1.95e-17: 88.2: 12.41
+	Hs
		209216 TCPE_HUMAN (1-541): 0: 637: 100.00		PRP4_HUMAN (445-595): 6.02e-15: 79.7: 8.64
+	Hs
		881865 TCPG_HUMAN (14-540): 0: 574: 33.15		GBB2_HUMAN (358-564): 1.19e-26: 113: 15.24
+	Hs
		881861 TCPG_HUMAN (14-540): 0: 574: 33.15		WDR5_HUMAN (446-596): 1.52e-21: 98.2: 8.44
+	Hs
		882014 TCPG_HUMAN (14-540): 0: 574: 33.15		WDR5B_HUMAN (438-596): 2.26e-21: 97.4: 10.49
+	Hs
		882075 TCPG_HUMAN (14-540): 0: 574: 33.15		FBXW7_HUMAN (93-288): 4.58e-20: 96.6: 13.85
+	Hs
		881906 TCPG_HUMAN (14-540): 0: 574: 33.15		DC1I2_HUMAN (266-576): 3.08e-18: 90.5: 10.62
+	Hs
		209218 TCPG_HUMAN (14-540): 0: 574: 33.15		PRP4_HUMAN (445-595): 6.02e-15: 79.7: 8.64