HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (EC 3.6.1.-) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: DC1I2 (Q13409)
Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)
Gene: DYNC1I2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	28718761, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 638
+	Hs
		156605 TCPE_HUMAN (1-541): 0: 637: 100.00		DC1I1_HUMAN (1-638): 4.52e-130: 398: 75.04
+	Hs
		881906 TCPG_HUMAN (14-540): 0: 574: 33.15		DC1I2_HUMAN (1-638): 2.56e-143: 432: 100.00
+	Hs
		156659 TCPH_HUMAN (12-539): 0: 572: 29.64		DC1I1_HUMAN (1-638): 4.52e-130: 398: 75.04
+	Hs
		876162 TCPE_HUMAN (1-541): 0: 637: 100.00		DNAI2_HUMAN (154-636): 1.77e-77: 260: 19.72
+	Hs
		882085 TCPG_HUMAN (14-540): 0: 574: 33.15		DC2I2_HUMAN (190-623): 5.1e-84: 275: 19.75
+	Hs
		875898 TCPE_HUMAN (1-541): 0: 637: 100.00		WDR5_HUMAN (368-626): 2.66e-62: 211: 16.60
+	Hs
		882148 TCPG_HUMAN (14-540): 0: 574: 33.15		DNAI2_HUMAN (154-636): 1.77e-77: 260: 19.72
+	Hs
		876146 TCPE_HUMAN (1-541): 0: 637: 100.00		TBL1Y_HUMAN (364-621): 5.09e-45: 169: 14.66
+	Hs
		881861 TCPG_HUMAN (14-540): 0: 574: 33.15		WDR5_HUMAN (368-626): 2.66e-62: 211: 16.60
+	Hs
		965190 TCPH_HUMAN (12-539): 0: 572: 29.64		WDR5_HUMAN (368-626): 2.66e-62: 211: 16.60
+	Hs
		876081 TCPE_HUMAN (1-541): 0: 637: 100.00		POC1B_HUMAN (199-446): 2.66e-28: 120: 9.62
+	Hs
		882014 TCPG_HUMAN (14-540): 0: 574: 33.15		WDR5B_HUMAN (157-509): 6.68e-49: 175: 15.51
+	Hs
		876199 TCPE_HUMAN (1-541): 0: 637: 100.00		NLE1_HUMAN (220-410): 3.59e-25: 111: 13.27
+	Hs
		875977 TCPE_HUMAN (1-541): 0: 637: 100.00		RBBP7_HUMAN (429-613): 3.41e-25: 110: 17.41
+	Hs
		882119 TCPG_HUMAN (14-540): 0: 574: 33.15		TBL1Y_HUMAN (364-621): 5.09e-45: 169: 14.66
+	Hs
		876070 TCPE_HUMAN (1-541): 0: 637: 100.00		POC1A_HUMAN (512-624): 4.51e-17: 85.6: 16.81
+	Hs
		845257 TCPG_HUMAN (14-540): 0: 574: 33.15		LIS1_HUMAN (472-631): 1.2e-31: 129: 16.88
+	Ce
		866358 TCPE_CAEEL (3-540): 0: 587: 68.40		LIN53_CAEEL (429-613): 2.09e-26: 114: 16.50
+	Hs
		882051 TCPG_HUMAN (14-540): 0: 574: 33.15		POC1B_HUMAN (199-446): 2.66e-28: 120: 9.62
+	Hs
		882038 TCPG_HUMAN (14-540): 0: 574: 33.15		POC1A_HUMAN (512-624): 4.51e-17: 85.6: 16.81