HitPredict

Interactor 1: PPE2 (O14830)
Serine/threonine-protein phosphatase with EF-hands 2 (PPEF-2) (EC 3.1.3.16)
Gene: PPEF2

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27880917
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 753 Hs			1 365
+	Hs
		156647 PPE2_HUMAN (1-753): 0: 719: 100.00		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	Hs
		858686 PPP5_HUMAN (321-559): 8.82e-67: 231: 22.18		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Mm
		1141237 PPP5_MOUSE (321-559): 2.58e-66: 229: 21.77		SGT1_MOUSE (1-365): 2.63e-76: 240: 74.25
+	Mm
		930630 PP2AA_MOUSE (362-550): 1.57e-78: 256: 21.24		PPP5_MOUSE (9-202): 3.13e-39: 147: 16.58
+	Hs
		906134 PP1A_HUMAN (359-543): 5.1e-84: 271: 20.21		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	Hs
		738048 PP1G_HUMAN (359-563): 1.32e-83: 270: 19.23		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	Hs
		906599 PP1B_HUMAN (359-546): 1.99e-83: 270: 19.37		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	Hs
		737763 PP1G_HUMAN (359-563): 1.32e-83: 270: 19.23		SPAG1_HUMAN (2-339): 1.63e-24: 107: 12.50
+	Mm
		1141207 PPP5_MOUSE (321-559): 2.58e-66: 229: 21.77		PPP5_MOUSE (9-202): 3.13e-39: 147: 16.58
+	Hs
		858598 PPP5_HUMAN (321-559): 8.82e-67: 231: 22.18		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Hs
		174681 PP1G_HUMAN (359-563): 1.32e-83: 270: 19.23		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Hs
		174743 PPP5_HUMAN (321-559): 8.82e-67: 231: 22.18		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Dm
		1366835 Q9VH81_DROME (291-555): 2.18e-63: 222: 21.17		Q9VPN5_DROME (1-321): 9.76e-18: 86: 10.98