Interactor 1: IKKB (O14920)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK-2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: IKBKB

Interactor 2: RS3 (P23396)
Small ribosomal subunit protein uS3 (40S ribosomal protein S3) (EC 4.2.99.18)
Gene: RPS3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 0.60 0.578

The method score is based on:

Property Details
Experiments 21399639
Identification Methods anti tag coimmunoprecipitation, protein kinase assay, anti bait coimmunoprecipitation
Interaction Type physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 756
Hs

1 243
+ Hs
+ Dm
+ Dm

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Last updated: 15 Jul 2024