HitPredict

Interactor 1: ML12B (O14950)
Myosin regulatory light chain 12B (MLC-2A) (MLC-2) (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) (SHUJUN-1)
Gene: MYL12B

Interactor 2: MYH10 (P35580)
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)
Gene: MYH10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 24981860, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~IQ, EF-hand_7~Myosin_head, EF-hand_7~Myosin_N
Common GO terms GO:0001725 - stress fiber
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005938 - cell cortex
GO:0008360 - regulation of cell shape
and 2 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 172
Hs

1 1976
+ Ce
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Ce
+ Ce
+ Hs
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024