Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.660

The method score is based on:

Property Details
Experiments 27107012, 35509083, unassigned3799
Identification Methods two hybrid, affinity chromatography technology, barcode fusion genetics two hybrid, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 736
Hs

1 568
+ Hs
+ Hs
+ Dm
+ Dm
+ Ce
+ Hs
+ Rn
+ Ce

Service provided by Combinatics, Japan

Last updated: 11Aug2025